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cis-Capsaicin - 95%, high purity , Vanilloid receptor agonist, CAS No.25775-90-0, Vanilloid receptor agonist

  • Moligand™
  • ≥95%
Item Number
C346860
Grouped product items
SKUSizeAvailabilityPrice Qty
C346860-10mg
10mg
In stock
$58.90
C346860-50mg
50mg
In stock
$187.90
C346860-100mg
100mg
In stock
$338.90
C346860-250mg
250mg
In stock
$761.90
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View related series
TRPV1 Activator

Basic Description

SynonymsZucapsaicin|25775-90-0|Civamide|cis-Capsaicin|(Z)-Capsaicin|(Z)-N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide|Civanex|(Z)-8-Methyl-N-vanillyl-6-nonenamide|(6Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide|(Z)-N-[(4-hydroxy-3-methoxyph
Specifications & PurityMoligand™, ≥95%
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeACTIVATOR, AGONIST
Mechanism of actionVanilloid receptor agonist

Product Properties

ALogP3.6

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TRPV1 Tclin Transient receptor potential cation channel subfamily V member 1 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GAA Tclin Lysosomal alpha-glucosidase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CASP1 Tchem Caspase-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TP53 Tchem Cellular tumor antigen p53 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488191950
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488191950
IUPAC Name (Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
INCHI InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6-
InChi Key YKPUWZUDDOIDPM-VURMDHGXSA-N
Canonical SMILES CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Isomeric SMILES CC(C)/C=C\CCCCC(=O)NCC1=CC(=C(C=C1)O)OC
PubChem CID 1548942
Molecular Weight 305.42

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
D23061440Certificate of AnalysisFeb 13, 2023 C346860
D23061441Certificate of AnalysisFeb 13, 2023 C346860
D23061443Certificate of AnalysisFeb 13, 2023 C346860
D23061447Certificate of AnalysisFeb 13, 2023 C346860
D23061448Certificate of AnalysisFeb 13, 2023 C346860
D23061450Certificate of AnalysisFeb 13, 2023 C346860
D23061451Certificate of AnalysisFeb 13, 2023 C346860
D23061454Certificate of AnalysisFeb 13, 2023 C346860

Chemical and Physical Properties

SensitivityLight sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H335:May cause respiratory irritation

H301:Toxic if swallowed

H318:Causes serious eye damage

H317:May cause an allergic skin reaction

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

Related Documents

 SDS

 Specification Sheet

References

1. Sałat K, Jakubowska A, Kulig K.  (2014)  Zucapsaicin for the treatment of neuropathic pain..  Expert Opin Investig Drugs,  23  (10): (1433-40).  [PMID:25171227]
2. Ann J, Kim HS, Thorat SA, Kim H, Ha HJ, Choi K, Kim YH, Kim M, Hwang SW, Pearce LV et al..  (2020)  Discovery of Nonpungent Transient Receptor Potential Vanilloid 1 (TRPV1) Agonist as Strong Topical Analgesic..  J Med Chem,  63  (1): (418-424).  [PMID:31702924]

Solution Calculators

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