| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| C295225-250mg | 250mg | In stock | $147.90 | |
| C295225-1g | 1g | In stock | $411.90 | |
| C295225-5g | 5g | In stock | $1,435.90 |
| Specifications & Purity | Moligand™, ≥99.5% |
|---|---|
| Biochemical and Physiological Mechanisms | Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.Potent, broad spectrum antineoplastic agent. Cytotoxic, crosslinks DNA to impair replication and transcription. Arrests cell cycle in G 2 /M phase. Antitumor, cros |
| Storage Temp | Protected from light,Room temperature,Argon charged |
| Shipped In | Normal |
| Grade | Moligand™ |
| Product Description | Product class Chemical properties Chemical formula H6N2Cl2Pt Empirical formula [Pt(NH3)2Cl2] Molecular weight 300.05 Metal Pt Theoretical metal content 65.02 Physical state crystalline Color Metal purity yellow 99.95 |
| INCHI | 1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2 |
|---|---|
| InChi Key | LXZZYRPGZAFOLE-UHFFFAOYSA-L |
| Canonical SMILES | N.N.Cl[Pt]Cl |
| WGK Germany | 3 |
| RTECS | TP2450000 |
| UN Number | 2928 |
| Packing Group | I |
| Molecular Weight | 300.1 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2314543 | Certificate of Analysis | Oct 21, 2023 | C295225 |
| K2314541 | Certificate of Analysis | Oct 21, 2023 | C295225 |
| K2314540 | Certificate of Analysis | Oct 21, 2023 | C295225 |
| H2412488 | Certificate of Analysis | Oct 21, 2023 | C295225 |
| K2314539 | Certificate of Analysis | Oct 21, 2023 | C295225 |
| K2314538 | Certificate of Analysis | Oct 21, 2023 | C295225 |
| K2314537 | Certificate of Analysis | Oct 21, 2023 | C295225 |
| J2316047 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| L2202051 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| L2201791 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| L2201739 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| J2309072 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| H2315307 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| F2314496 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| D2323932 | Certificate of Analysis | Nov 03, 2022 | C295225 |
| C2221080 | Certificate of Analysis | Mar 31, 2022 | C295225 |
| A2214408 | Certificate of Analysis | Jan 03, 2022 | C295225 |
| A2214410 | Certificate of Analysis | Jan 03, 2022 | C295225 |
| A2214409 | Certificate of Analysis | Jan 03, 2022 | C295225 |
| Solubility | Soluble in DMSO (25 mg/ml), water (0.25 g/100ml) at 25 °C, ethanol (<1 mg/ml) at 25 °C, and DMF (16 mg/ml) |
|---|---|
| Sensitivity | Moisture sensitive & Light sensitive |
| Melt Point(°C) | 270°C |
| Pictogram(s) | GHS06, GHS08 |
|---|---|
| Signal | Danger |
| Hazard Statements | H319:Causes serious eye irritation H300:Fatal if swallowed H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H340:May cause genetic defects H350:May cause cancer H370:Causes damage to organs H316:Causes mild skin irritation H362:May cause harm to breast-fed children |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER/doctor/... P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P201:Obtain special instructions before use. P337+P313:IF eye irritation persists: Get medical advice/attention. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P308+P311:IF exposed or concerned: Call a POISON CENTER/doctor/... P202:Do not handle until all safety precautions have been read and understood. P330:Rinse mouth. |
| WGK Germany | 3 |
| RTECS | TP2450000 |
| Class | 6.1, 8 |
| Merck Index | 2317 |
| RIDADR | UN 3288 6.1 / PGII |
Starting at $33.90
| 1. Jiang Hao, Tian Hailong, Wang Zhihan, Li Bowen, Chen Rui, Luo Kangjia, Lu Shuaijun, Nice Edouard C., Zhang Wei, Huang Canhua, Zhou Yuping, Zheng Shaojiang, Gao Feng. (2023) Laser-activatable oxygen self-supplying nanoplatform for efficiently overcoming colorectal cancer resistance by enhanced ferroptosis and alleviated hypoxic microenvironment. Biomaterials Research, 27 (1): (1-20). [PMID:37742011] |
| 2. Leyi Fang, Xiao-Tong Pan, Kang Liu, Dechen Jiang, Deju Ye, Li-Na Ji, Kang Wang, Xing-Hua Xia. (2023) Surface-Roughened SERS-Active Single Silver Nanowire for Simultaneous Detection of Intracellular and Extracellular pHs. ACS Applied Materials & Interfaces, 15 (17): (20677–20685). [PMID:37071781] |
| 3. Yunfan Liu, Jiazhou Zhai, Fei Qin, Liping Gao, Yongxin She, Mengqiang Wang. (2023) Protective role of polyphenol extract from highland barley against cisplatin-induced renal toxicity and mitochondrial damage in rats. FOOD SCIENCE AND TECHNOLOGY RESEARCH, [PMID:] |
| 4. Yi Xiao, Haomin Yi, Jingzhi Zhu, Suhua Chen, Guofang Wang, Yilong Liao, Yuanyuan Lei, Liyin Chen, Xingcai Zhang, Fangfu Ye. (2023) Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme. Bioactive Materials, 23 (45). [PMID:36406255] |
| 5. Zhou Yafu, Yan Jianhua, Chen Huiguo, Zhou Wenwu, Yang Jinsong. (2022) MicroRNA-133a-3p Inhibits Lung Adenocarcinoma Development and Cisplatin Resistance through Targeting GINS4. CELLS TISSUES ORGANS, (1-12). [PMID:36273455] |
| 6. Xue-qi Liu, Ming-ming Liu, Ling Jiang, Li Gao, Yao Zhang, Yue-bo Huang, Xian Wang, Wei Zhu, Han-xu Zeng, Xiao-ming Meng, Yong-gui Wu. (2022) A novel small molecule Hsp90 inhibitor, C-316-1, attenuates acute kidney injury by suppressing RIPK1-mediated inflammation and necroptosis. INTERNATIONAL IMMUNOPHARMACOLOGY, 108 (108849). [PMID:35588657] |
| 1. Jiang Hao, Tian Hailong, Wang Zhihan, Li Bowen, Chen Rui, Luo Kangjia, Lu Shuaijun, Nice Edouard C., Zhang Wei, Huang Canhua, Zhou Yuping, Zheng Shaojiang, Gao Feng. (2023) Laser-activatable oxygen self-supplying nanoplatform for efficiently overcoming colorectal cancer resistance by enhanced ferroptosis and alleviated hypoxic microenvironment. Biomaterials Research, 27 (1): (1-20). [PMID:37742011] |
| 2. Leyi Fang, Xiao-Tong Pan, Kang Liu, Dechen Jiang, Deju Ye, Li-Na Ji, Kang Wang, Xing-Hua Xia. (2023) Surface-Roughened SERS-Active Single Silver Nanowire for Simultaneous Detection of Intracellular and Extracellular pHs. ACS Applied Materials & Interfaces, 15 (17): (20677–20685). [PMID:37071781] |
| 3. Yunfan Liu, Jiazhou Zhai, Fei Qin, Liping Gao, Yongxin She, Mengqiang Wang. (2023) Protective role of polyphenol extract from highland barley against cisplatin-induced renal toxicity and mitochondrial damage in rats. FOOD SCIENCE AND TECHNOLOGY RESEARCH, [PMID:] |
| 4. Yi Xiao, Haomin Yi, Jingzhi Zhu, Suhua Chen, Guofang Wang, Yilong Liao, Yuanyuan Lei, Liyin Chen, Xingcai Zhang, Fangfu Ye. (2023) Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme. Bioactive Materials, 23 (45). [PMID:36406255] |
| 5. Zhou Yafu, Yan Jianhua, Chen Huiguo, Zhou Wenwu, Yang Jinsong. (2022) MicroRNA-133a-3p Inhibits Lung Adenocarcinoma Development and Cisplatin Resistance through Targeting GINS4. CELLS TISSUES ORGANS, (1-12). [PMID:36273455] |
| 6. Xue-qi Liu, Ming-ming Liu, Ling Jiang, Li Gao, Yao Zhang, Yue-bo Huang, Xian Wang, Wei Zhu, Han-xu Zeng, Xiao-ming Meng, Yong-gui Wu. (2022) A novel small molecule Hsp90 inhibitor, C-316-1, attenuates acute kidney injury by suppressing RIPK1-mediated inflammation and necroptosis. INTERNATIONAL IMMUNOPHARMACOLOGY, 108 (108849). [PMID:35588657] |
