Grouped product items

SKU

Size

Availability

Price

Qty

C347980-1mg

1mg

Available within 4-8 weeks(?)

$58.90

C347980-5mg

5mg

Available within 4-8 weeks(?)

$248.90

C347980-25mg

25mg

Available within 4-8 weeks(?)

$925.90

C347980-100mg

100mg

Available within 4-8 weeks(?)

$3,333.90

Basic Description

Synonyms	cloprostenol\|(+)-Cloprostenol\|54276-21-0\|40665-92-7\|Racemic cloprostenol\|Cloprostenolum\|Oestrophane\|Dalmazin\|Estrophan\|Estrophane\|R-Cloprostenol\|Dalmaprost D\|(+-)-Cloprostenol\|(+/-)-Cloprostenol\|Cloprostenol, (+)-\|D-Cloprostenol\|ICI 80996\|EINECS 255-028-8
Specifications & Purity	Moligand™, ≥97%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of DP 1 receptor;Agonist of EP 1 receptor;Agonist of EP 3 receptor;Agonist of FP receptor;Agonist of TP receptor
Product Description	(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α), a PGF2αR (FP receptor) agonist and a potent water diluent in hamsters and rats. (+)-Chloroprostenol is the optically active 15(R) enantiomer of chloroprenol and possesses most of the biological activity. The potency of chloroprenol in termination of pregnancy in hamsters and rats, respectively, is that of PGF2α 200-fold and 100-fold without the side effects associated with PGF2α.

Associated Targets

CX3CR1 Tchem CX3C chemokine receptor 1 0 Activities

Discover Target: CX3CR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GPR35 Tchem G-protein coupled receptor 35 0 Activities

Discover Target: GPR35

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BRD4 Tchem Bromodomain-containing protein 4 0 Activities

Discover Target: BRD4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDK2 Tchem Cyclin-dependent kinase 2 0 Activities

Discover Target: CDK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FTL Tbio Ferritin light chain 0 Activities

Discover Target: FTL

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FFAR4 Tchem Free fatty acid receptor 4 0 Activities

Discover Target: FFAR4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FPR2 Tchem N-formyl peptide receptor 2 0 Activities

Discover Target: FPR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FGFR3 Tclin Fibroblast growth factor receptor 3 0 Activities

Discover Target: FGFR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CSNK1D Tchem Casein kinase I isoform delta 0 Activities

Discover Target: CSNK1D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

S1PR1 Tclin Sphingosine 1-phosphate receptor 1 0 Activities

Discover Target: S1PR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRIM24 Tchem Transcription intermediary factor 1-alpha 0 Activities

Discover Target: TRIM24

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGER2 Tclin Prostaglandin E2 receptor EP2 subtype 0 Activities

Discover Target: PTGER2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGDR Tclin Prostaglandin D2 receptor 1 Activities

Discover Target: PTGDR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGER4 Tclin Prostaglandin E2 receptor EP4 subtype 0 Activities

Discover Target: PTGER4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGER1 Tclin Prostaglandin E2 receptor EP1 subtype 0 Activities

Discover Target: PTGER1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGFR Tclin Prostaglandin F2-alpha receptor 5 Activities

Discover Target: PTGFR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGIR Tclin Prostacyclin receptor 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGER3 Tclin Prostaglandin E2 receptor EP3 subtype 2 Activities

Discover Target: PTGER3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C5AR1 Tclin C5a anaphylatoxin chemotactic receptor 1 0 Activities

Discover Target: C5AR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

BRPF1 Tchem Peregrin 0 Activities

Discover Target: BRPF1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AURKA Tchem Aurora kinase A 0 Activities

Discover Target: AURKA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRB2 Tclin Beta-2 adrenergic receptor 0 Activities

Discover Target: ADRB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

APLNR Tchem Apelin receptor 0 Activities

Discover Target: APLNR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

Discover Target: ABL1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

Discover Target: ADRA2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADGRF1 Tbio Adhesion G-protein coupled receptor F1 0 Activities

Discover Target: ADGRF1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AGTR1 Tclin Type-1 angiotensin II receptor 0 Activities

Discover Target: AGTR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TBXA2R Tclin Thromboxane A2 receptor 1 Activities

Discover Target: TBXA2R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

THRB Tclin Thyroid hormone receptor beta 0 Activities

Discover Target: THRB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GSK3B Tclin Glycogen synthase kinase-3 beta 0 Activities

Discover Target: GSK3B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GPR119 Tclin Glucose-dependent insulinotropic receptor 0 Activities

Discover Target: GPR119

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

Discover Target: GLP1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Discover Target: MAPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(Z)-7-[(1R,2R,3R,5S)-2-[(E,3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid
INCHI	InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
InChi Key	VJGGHXVGBSZVMZ-QIZQQNKQSA-N
Canonical SMILES	C1C(C(C(C1O)C=CC(COC2=CC(=CC=C2)Cl)O)CC=CCCCC(=O)O)O
Isomeric SMILES	C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/[C@H](COC2=CC(=CC=C2)Cl)O)C/C=C\CCCC(=O)O)O
PubChem CID	5311053
Molecular Weight	424.9

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot Number	Certificate Type	Date	Item
F2204322	Certificate of Analysis	Mar 24, 2022	C347980
F2204323	Certificate of Analysis	Mar 24, 2022	C347980
F2204324	Certificate of Analysis	Mar 24, 2022	C347980
F2204325	Certificate of Analysis	Mar 24, 2022	C347980

Chemical and Physical Properties

Solubility	DMF: >100 mg/ml (from Fluprostenol)；DMSO: >100 mg/ml (from Fluprostenol；Ethanol: >100 mg/ml (from Fluprostenol)；PBS pH 7.2: >16 mg/ml (from Fluprostenol)
Boil Point(°C)	78° C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H302:Harmful if swallowed H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled H360:May damage fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P284:[In case of inadequate ventilation] Wear respiratory protection. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

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SKU	Size	Availability	Price
C347980-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$58.90
C347980-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$248.90
C347980-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$925.90
C347980-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$3,333.90

(+)-Cloprostenol - 97%, high purity , CAS No.54276-21-0, Agonist of DP 1 receptor;Agonist of EP 1 receptor;Agonist of EP 3 receptor;Agonist of FP receptor;Agonist of TP receptor

Basic Description

Associated Targets

CX3CR1 Tchem CX3C chemokine receptor 1 0 Activities

GPR35 Tchem G-protein coupled receptor 35 0 Activities

BRD4 Tchem Bromodomain-containing protein 4 0 Activities

CDK2 Tchem Cyclin-dependent kinase 2 0 Activities

FTL Tbio Ferritin light chain 0 Activities

FFAR4 Tchem Free fatty acid receptor 4 0 Activities

HDAC6 Tclin Histone deacetylase 6 0 Activities

FPR2 Tchem N-formyl peptide receptor 2 0 Activities

FGFR3 Tclin Fibroblast growth factor receptor 3 0 Activities

CSNK1D Tchem Casein kinase I isoform delta 0 Activities

S1PR1 Tclin Sphingosine 1-phosphate receptor 1 0 Activities

TRIM24 Tchem Transcription intermediary factor 1-alpha 0 Activities

PTGER2 Tclin Prostaglandin E2 receptor EP2 subtype 0 Activities

PTGDR Tclin Prostaglandin D2 receptor 1 Activities

PTGER4 Tclin Prostaglandin E2 receptor EP4 subtype 0 Activities

PTGER1 Tclin Prostaglandin E2 receptor EP1 subtype 0 Activities

PTGFR Tclin Prostaglandin F2-alpha receptor 5 Activities

PTGIR Tclin Prostacyclin receptor 0 Activities

PTGER3 Tclin Prostaglandin E2 receptor EP3 subtype 2 Activities

C5AR1 Tclin C5a anaphylatoxin chemotactic receptor 1 0 Activities

BRPF1 Tchem Peregrin 0 Activities

AURKA Tchem Aurora kinase A 0 Activities

ADRB2 Tclin Beta-2 adrenergic receptor 0 Activities

APLNR Tchem Apelin receptor 0 Activities

ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

ADGRF1 Tbio Adhesion G-protein coupled receptor F1 0 Activities

AGTR1 Tclin Type-1 angiotensin II receptor 0 Activities

TBXA2R Tclin Thromboxane A2 receptor 1 Activities

THRB Tclin Thyroid hormone receptor beta 0 Activities

GSK3B Tclin Glycogen synthase kinase-3 beta 0 Activities

GPR119 Tclin Glucose-dependent insulinotropic receptor 0 Activities

GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

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