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CMP-Sialic Acid, Monosodium Salt - ≥85%, high purity , CAS No.3063-71-6

  • ≥85%
Item Number
C350394
Grouped product items
SKUSizeAvailabilityPrice Qty
C350394-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$56.90
C350394-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$212.90

a toxin/gonococci protector; blood regulator

Basic Description

SynonymsCmp-nana|CMP acetylneuraminic acid|3063-71-6|(2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid|T8I6M8AXA0|CMP-N-ac
Specifications & Purity≥85%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

CMP-sialic acid, Monosodium salt is the active form of sialic acid. In mammalian cells it has been shown to be required for the biosynthesis of sialic acid-containing complex carbohydrates. Loss of CMP sialic acid, Monosodium salt production or the feed back inhibitor of CMP-sialic acid has lead to gram scale production of sialic acid by GLCNE (GNE, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase). The compound has demonstrated the ability to neutralize various toxins through masking binding sites. CMP-sialic acid, Monosodium salt has also provided protection against gonococci by siaylation of Gal beta 1-4GlcNAc group. Catalyzed through a surface sialyl-transferase, CMP-Sialic Acid, Monosodium Salt enhanced the responsiveness of insulin. The compound has also displayed function in blood protein half-life regulation, protection against glycoprotein lysis and cellular adhesion. CMP-Sialic Acid, Monosodium Salt is a substrate of Sialyltransferase.

Names and Identifiers

IUPAC Name (2R,4S,5R,6R)-5-acetamido-2-[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid
INCHI InChI=1S/C20H31N4O16P/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34)/t8-,9?,10+,12+,13?,14+,15+,16+,17+,20+/m0/s1
InChi Key TXCIAUNLDRJGJZ-HAOOPCFNSA-N
Canonical SMILES CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OP(=O)(O)OCC2C(C(C(O2)N3C=CC(=NC3=O)N)O)O)O
Isomeric SMILES CC(=O)N[C@@H]1[C@H](C[C@](O[C@H]1C(C(CO)O)O)(C(=O)O)OP(=O)(O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=NC3=O)N)O)O)O
PubChem CID 18292
Molecular Weight 636.43

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water.

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