| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| C334947-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $237.90 |
a derfivative of Colchicine
| Synonyms | Colchicine Methanethiosulfonate|1217821-52-7|3-methylsulfonylsulfanyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]propanamide|DTXSID00652528|AKOS030243134|J-004666|S-(3-Oxo-3-{[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahyd |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Methanethiosulfonate is a derfivative of Colchicine which is an antimitotic agent that disrupts microtubles by binding to Tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of Tubulin. Induces apoptosis. |
| IUPAC Name | 3-methylsulfonylsulfanyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]propanamide |
|---|---|
| INCHI | InChI=1S/C24H29NO8S2/c1-30-19-9-7-15-16(13-18(19)26)17(25-21(27)10-11-34-35(5,28)29)8-6-14-12-20(31-2)23(32-3)24(33-4)22(14)15/h7,9,12-13,17H,6,8,10-11H2,1-5H3,(H,25,27)/t17-/m0/s1 |
| InChi Key | KZMCZFBQMMHSRF-KRWDZBQOSA-N |
| Canonical SMILES | COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)CCSS(=O)(=O)C |
| Isomeric SMILES | COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)CCSS(=O)(=O)C |
| PubChem CID | 29976389 |
| Molecular Weight | 523.62 |
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| Solubility | Soluble in Chloroform, Dichloromethane, DMF, DMSO, Ethanol, Ethyl Acetate and Methanol |
|---|---|
| Melt Point(°C) | 119-120°C (lit.) |
