Colchicine Methanethiosulfonate , CAS No.1217821-52-7

Item Number
C334947
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C334947-5mg
5mg
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a derfivative of Colchicine

Basic Description

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Methanethiosulfonate is a derfivative of Colchicine which is an antimitotic agent that disrupts microtubles by binding to Tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of Tubulin. Induces apoptosis.

Names and Identifiers

IUPAC Name 3-methylsulfonylsulfanyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]propanamide
INCHI InChI=1S/C24H29NO8S2/c1-30-19-9-7-15-16(13-18(19)26)17(25-21(27)10-11-34-35(5,28)29)8-6-14-12-20(31-2)23(32-3)24(33-4)22(14)15/h7,9,12-13,17H,6,8,10-11H2,1-5H3,(H,25,27)/t17-/m0/s1
InChi Key KZMCZFBQMMHSRF-KRWDZBQOSA-N
Canonical SMILES COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)CCSS(=O)(=O)C
Isomeric SMILES COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)CCSS(=O)(=O)C
PubChem CID 29976389
Molecular Weight 523.62

Certificates

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Chemical and Physical Properties

SolubilitySoluble in Chloroform, Dichloromethane, DMF, DMSO, Ethanol, Ethyl Acetate and Methanol
Melt Point(°C)119-120°C (lit.)

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