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Colchicine Methanethiosulfonate , CAS No.1217821-52-7
a derfivative of Colchicine
Basic Description Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Methanethiosulfonate is a derfivative of Colchicine which is an antimitotic agent that disrupts microtubles by binding to Tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of Tubulin. Induces apoptosis.
Names and Identifiers IUPAC Name 3-methylsulfonylsulfanyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]propanamide INCHI InChI=1S/C24H29NO8S2/c1-30-19-9-7-15-16(13-18(19)26)17(25-21(27)10-11-34-35(5,28)29)8-6-14-12-20(31-2)23(32-3)24(33-4)22(14)15/h7,9,12-13,17H,6,8,10-11H2,1-5H3,(H,25,27)/t17-/m0/s1 InChi Key KZMCZFBQMMHSRF-KRWDZBQOSA-N Canonical SMILES COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)CCSS(=O)(=O)C Isomeric SMILES COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)CCSS(=O)(=O)C PubChem CID 29976389 Molecular Weight 523.62
Chemical and Physical Properties Solubility Soluble in Chloroform, Dichloromethane, DMF, DMSO, Ethanol, Ethyl Acetate and Methanol Melt Point(°C) 119-120°C (lit.)
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