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Collagenase from Clostridium histolyticum

  • High Purity
    •
  • purified by chromatography, Type VII,≥4 FALGPA units/mg solid, lyophilized powder,≥700 CDU/mg solid (CDU = collagen digestion units)
Item Number
C754919
Grouped product items
SKUSizeAvailabilityPrice Qty
C754919-1.5KU
1.5KU
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$88.90
C754919-3KU
3KU
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$155.90
C754919-7.5KU
7.5KU
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$307.90
C754919-15KU
15KU
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$569.90
C754919-60KU
60KU
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,809.90
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Basic Description

Specifications & PurityHigh Purity, purified by chromatography, Type VII,≥4 FALGPA units/mg solid, lyophilized powder,≥700 CDU/mg solid (CDU = collagen digestion units)
Biochemical and Physiological MechanismsEffective release of cells from tissue requires the action of both collagenase enzymes and the neutral protease. Collagenase is activated by four gram atom calcium (Ca2+) per mole enzyme. The culture filtrate is thought to contain at least 7 different pro
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeHigh Purity
Product DescriptionCollagenase has been used in the preparation of arterial tissue for the study of advanced glycosylation end products (AGE). The enzyme has also been used along with other proteases for the disaggregation of human tumor, mouse kidney, human brain, lung epithelium and many other tissues. It is also effective in liver and kidney perfusion studies, digestion of pancreas, and isolation of nonparenchymal hepatocytes.

Names and Identifiers

Enzyme Commission Number3.4.24.3(BRENDA,IUBMB)
Isomeric SMILES CCCCCCCC[C@H]1CC[C@@]2([C@@]1(CC[C@]3(C2CC[C@@]4([C@@]3(CC5=C(C4)N=C6C[C@]7([C@@](CCC8[C@@]7(CC[C@]9([C@]8(CC[C@@H]9CCCCCCCC)C)C)C)(CC6=N5)C)C)C)C)C)C)C
WGK Germany 1
PubChem CID 44384985

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityTESCA buffer (50 mM TES, 0.36 mM Calcium chloride, pH 7.4): soluble 0.05-0.1 mg/mL at 37 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08
Signal Warning
Hazard Statements

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P501:Dispose of contents/container to ...

P284:[In case of inadequate ventilation] Wear respiratory protection.

WGK Germany 1

Related Documents

 SDS

 Specification Sheet

Solution Calculators

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