| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| C655749-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $715.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein ( C5 ). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) depositi |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein ( C5 ). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC 50 of 0.77 µM. |
| Canonical SMILES | CC(C)CCCOC1=C(C=C(C(=C1)NC(=O)NC(C)C2=CC=CC=C2OC)C(=O)O)OC |
|---|---|
| Molecular Weight | 444.52 |
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