Basic Description

Synonyms	COPTISINE CHLORIDE\|6020-18-4\|Coptisine, chloride\|Coptisine (chloride)\|Coptisine hydrochloride\|Coptisin Chloride\|NSC-119754\|4RSB8UY88E\|Bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium, 6,7-dihydro-, chloride\|6020-18-4 (chloride)\|Berbinium, 7,8,13,13a-tetra
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Description Coptisine, a cytotoxic alkaloid found in Chinese goldthread, is related to berberine. It has been analyzed as a cytotoxic agent in heptoma and leukemic cells and is reported to block cell cycle progression.

Associated Targets

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	5,7,17,19-tetraoxa-13-azoniahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaene;chloride
INCHI	InChI=1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;/h1-2,5-8H,3-4,9-10H2;1H/q+1;/p-1
InChi Key	LUXPUVKJHVUJAV-UHFFFAOYSA-M
Canonical SMILES	C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6.[Cl-]
Isomeric SMILES	C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6.[Cl-]
PubChem CID	72321
Molecular Weight	355.77

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4 results found

Lot Number	Certificate Type	Date	Item
H2421181	Certificate of Analysis	Aug 05, 2024	C465003
H2421182	Certificate of Analysis	Aug 05, 2024	C465003
H2421183	Certificate of Analysis	Aug 05, 2024	C465003
H2421184	Certificate of Analysis	Aug 05, 2024	C465003

Sensitivity	air & moisture sensitive
Melt Point(°C)	218°C

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H311:Toxic in contact with skin H373:Causes damage to organs through prolonged or repeated exposure H330:Fatal if inhaled
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.

1. Sabyasachi Chatterjee, Gopinatha Suresh Kumar,. (2017-04-14) Small molecule induced poly(A) single strand to self-structure conformational switching: evidence for the prominent role of H-bonding interactions.. Molecular bioSystems, 13 ((5)): ( 1000-1009 ). [PMID:28405661]

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SKU	Size	Availability	Price	Qty
C465003-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$182.90
C465003-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$414.90