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Cornuside - 98%, high purity , CAS No.131189-57-6

≥98%

CAS#: 131189-57-6
Formula: C₂₄H₃₀O₁₄
Molecular Weight: 542.49
MDL number: MFCD21606970
PubChem CID: 11228694

Item Number

C463785

Grouped product items
SKU	Size	Availability	Price
C463785-1mg	1mg	In stock	$117.90
C463785-5mg	5mg	In stock	$331.90
C463785-10mg	10mg	In stock	$523.90
C463785-25mg	25mg	In stock	$1,179.90
C463785-50mg	50mg	In stock	$2,122.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Cornuside is a Iridoid glycoside isolated from the fruit of Cornus officinalis Sieb. et Zucc. Cornus officinalis is a traditional oriental medicine, which can be used to study inflammatory diseases and promote blood circulation. Cornuside downregulates MA
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Description Natural product derived from plant source.

Names and Identifiers

IUPAC Name	methyl (2S,3R,4S)-3-ethenyl-4-[2-(3,4,5-trihydroxybenzoyl)oxyethyl]-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylate
INCHI	InChI=1S/C24H30O14/c1-3-11-12(4-5-35-21(32)10-6-14(26)17(28)15(27)7-10)13(22(33)34-2)9-36-23(11)38-24-20(31)19(30)18(29)16(8-25)37-24/h3,6-7,9,11-12,16,18-20,23-31H,1,4-5,8H2,2H3/t11-,12+,16-,18-,19+,20-,23+,24+/m1/s1
InChi Key	SMTKSCGLXONVGL-UPIRYGIPSA-N
Canonical SMILES	COC(=O)C1=COC(C(C1CCOC(=O)C2=CC(=C(C(=C2)O)O)O)C=C)OC3C(C(C(C(O3)CO)O)O)O
Isomeric SMILES	COC(=O)C1=CO[C@H]([C@@H]([C@@H]1CCOC(=O)C2=CC(=C(C(=C2)O)O)O)C=C)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O
PubChem CID	11228694
Molecular Weight	542.49

Certificates

Certificate of Analysis(COA)

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10 results found

Lot Number	Certificate Type	Date	Item
H2301560	Certificate of Analysis	Jul 07, 2023	C463785
H2301561	Certificate of Analysis	Jul 07, 2023	C463785
H2301563	Certificate of Analysis	Jul 07, 2023	C463785
H2301567	Certificate of Analysis	Jul 07, 2023	C463785
H2301568	Certificate of Analysis	Jul 07, 2023	C463785
H2301571	Certificate of Analysis	Jul 07, 2023	C463785
H2301572	Certificate of Analysis	Jul 07, 2023	C463785
H2301573	Certificate of Analysis	Jul 07, 2023	C463785
H2301579	Certificate of Analysis	Jul 07, 2023	C463785
H2301650	Certificate of Analysis	Jul 07, 2023	C463785

References

1. Dae Gill Kang,Mi Kyoung Moon,An Sook Lee,Tae Oh Kwon,Jin Sook Kim,Ho Sub Lee. (2007-09-11) Cornuside suppresses cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells.. Biological & pharmaceutical bulletin, 30 ((9)): (1796-1799). [PMID:17827743]
2. Weifeng Du,Hao Cai,Mingyan Wang,Xia Ding,Huan Yang,Baochang Cai. (2008-06-14) Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography.. Journal of pharmaceutical and biomedical analysis, 48 ((1)): (194-197). [PMID:18550316]
3. Wang-Lin Jiang,Xi-Guang Chen,Hai-Bo Zhu,Jing-Wei Tian. (2009-03-06) Effect of cornuside on experimental sepsis.. Planta medica, 75 ((6)): (614-619). [PMID:19263342]
4. Shun Zong Song,Yun Ho Choi,Guang Yu Jin,Guang Zhao Li,Guang Hai Yan. (2011-04-23) Protective effect of cornuside against carbon tetrachloride-induced acute hepatic injury.. Bioscience, biotechnology, and biochemistry, 75 ((4)): (656-661). [PMID:21512227]
5. Yun Ho Choi,Guang Yu Jin,Guang Zhao Li,Guang Hai Yan. (2011-07-02) Cornuside suppresses lipopolysaccharide-induced inflammatory mediators by inhibiting nuclear factor-kappa B activation in RAW 264.7 macrophages.. Biological & pharmaceutical bulletin, 34 ((7)): (959-966). [PMID:21719998]
6. Juan-ni He,Xiao Liu,Zhao-li Mou,Han-ying Zhan,Zhi-qi Zhang. (2011-11-10) [Optimization of microwave-assisted extraction with RSM and HPLC determination for three iridoid glycosides in Cornus officinalis].. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34 ((7)): (1118-1122). [PMID:22066408]
7. S P Zhao,Z Xue. (1992-01-01) [Studies on the chemical constituents of Cornus officinalis Sieb et Zucc].. Yao xue xue bao = Acta pharmaceutica Sinica, 27 ((11)): (845-848). [PMID:1341909]
8. Dae Gill Kang,Deok Ho Choi,Jun Kyoung Lee,Yun Jeong Lee,Mi Kyoung Moon,Sun Nye Yang,Tae Oh Kwon,Ji Woong Kwon,Jin Sook Kim,Ho Sub Lee. (2007-10-11) Endothelial NO/cGMP-dependent vascular relaxation of cornuside isolated from the fruit of Cornus officinalis.. Planta medica, 73 ((14)): (1436-1440). [PMID:17926269]
9. Wang-Lin Jiang,Xi-Guang Chen,Hai-Bo Zhu,Jian Hou,Jing-Wei Tian. (2009-08-22) Cornuside attenuates apoptosis and ameliorates mitochondrial energy metabolism in rat cortical neurons.. Pharmacology, 84 ((3)): (162-170). [PMID:19696522]
10. Wang-Lin Jiang,Shu-Min Zhang,Xue-Xi Tang,Hong-Zhan Liu. (2010-08-27) Protective roles of cornuside in acute myocardial ischemia and reperfusion injury in rats.. Phytomedicine : international journal of phytotherapy and phytopharmacology, 18 ((4)): (266-271). [PMID:20739159]

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Cornuside - 98%, high purity , CAS No.131189-57-6

Basic Description

Mechanisms of Action