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SKU | Size | Availability | Price | Qty |
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C274856-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $26.90 | |
C274856-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $56.90 | |
C274856-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $127.90 | |
C274856-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $225.90 | |
C274856-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $444.90 |
Highly potent, selective 5-HT 1B agonist
Synonyms | CP 94253 hydrochloride|845861-39-4|CP94253 (hydrochloride)|CP94253 hydrochloride|5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE hydrochloride|5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine hydrochloride|5-pr |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Highly potent and selective 5-HT 1B agonist (K i = 2.0 nM compared to values of 89 (5-HT 1A ), 860 (5-HT 1C ), 49 (5-HT 1D ) and 1600 nM (5-HT 2 )). Shows many behavioural effects, reducing aggression and food intake. |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | CP94253 hydrochloride is a potent and selective agonist of 5-HT1B receptor (Ki= 2 nM in a radioligand binding assay).Ki values for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors are 89, 49, 860, and 1600 nM respectively[1]. CP94253 hydrochloride is centrally active upon systemic administration in vivo. |
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IUPAC Name | 5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine;hydrochloride |
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INCHI | InChI=1S/C15H19N3O.ClH/c1-2-9-19-14-4-3-13-15(18-14)12(10-17-13)11-5-7-16-8-6-11;/h3-5,10,16-17H,2,6-9H2,1H3;1H |
InChi Key | PIIOXKQIZCVXMD-UHFFFAOYSA-N |
Canonical SMILES | CCCOC1=NC2=C(C=C1)NC=C2C3=CCNCC3.Cl |
Isomeric SMILES | CCCOC1=NC2=C(C=C1)NC=C2C3=CCNCC3.Cl |
Alternate CAS | 131084-35-0 |
PubChem CID | 11652258 |
Molecular Weight | 293.79 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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E2422194 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422195 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422196 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422197 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422198 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422199 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422200 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422201 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422202 | Certificate of Analysis | Feb 23, 2024 | C274856 |
E2422203 | Certificate of Analysis | Feb 23, 2024 | C274856 |
Solubility | Soluble in water to 100 mM |
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Sensitivity | Moisture sensitive |