JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

CR6086 , CAS No.C609596, Antagonist of EP 4 receptor

Item Number

C609596

Grouped product items
SKU	Size	Availability	Price	Qty
C609596-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$560.90
C609596-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,800.90

View related series

Basic Description

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	4-{1-[(5R)-6-{[4-(trifluoromethyl)phenyl]methyl}-6-azaspiro[2.5]octane-5-amido]cyclopropyl}benzoic acid
INCHI	InChI=1S/C26H27F3N2O3/c27-26(28,29)20-5-1-17(2-6-20)16-31-14-13-24(9-10-24)15-21(31)22(32)30-25(11-12-25)19-7-3-18(4-8-19)23(33)34/h1-8,21H,9-16H2,(H,30,32)(H,33,34)/t21-/m1/s1
InChi Key	CADWTPLFEZSAHM-OAQYLSRUSA-N
Canonical SMILES	O=C([C@H]1CC2(CCN1Cc1ccc(cc1)C(F)(F)F)CC2)NC1(CC1)c1ccc(cc1)C(=O)O
PubChem CID	133081958

GPCRdb Ligand	CR6086
PubChem CID	133081958

Enter Lot Number to search for COA:

1. Caselli G, Bonazzi A, Lanza M, Ferrari F, Maggioni D, Ferioli C, Giambelli R, Comi E, Zerbi S, Perrella M et al.. (2018) Pharmacological characterisation of CR6086, a potent prostaglandin E₂receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug.. Arthritis Res Ther, 20 (1): (39). [PMID:29490676]

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.