CTX1 - 97%, high purity , CAS No.501935-96-2

Item Number

C646180

Grouped product items
SKU	Size	Availability	Price
C646180-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$83.90
C646180-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$133.90
C646180-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$243.90
C646180-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$544.90

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Basic Description

Specifications & Purity	97%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	CTX1 is a p53 activator that overcomes HdmX-mediated p53 repression. CTX1 exhibits potent anti-cancer activity in a mouse acute myeloid leukemia (AML) model system In Vitro CTX1 binds directly to HdmX to prevent p53-HdmX complex formation, resulting in the rapidly induction of p53 in a DNA damage-independent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo CTX1 ( (30 mg/kg; i.p.; five days a week; for 3 weeks) significantly enhances the survival of mice in AML model system . CTX1 exhibited significant anti-cancer activity alone as well as in combination with nutlin-3 . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:p53

Names and Identifiers

IUPAC Name	3,6-diaminoacridine-9-carbonitrile
INCHI	InChI=1S/C14H10N4/c15-7-12-10-3-1-8(16)5-13(10)18-14-6-9(17)2-4-11(12)14/h1-6H,16-17H2
InChi Key	PUMGFEMNXBLDKD-UHFFFAOYSA-N
Canonical SMILES	C1=CC2=C(C=C1N)N=C3C=C(C=CC3=C2C#N)N
Isomeric SMILES	C1=CC2=C(C=C1N)N=C3C=C(C=CC3=C2C#N)N
PubChem CID	435038
Molecular Weight	234.26

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Basic Description