Cucurbitacin E - >99%, high purity , CAS No.18444-66-1

Item Number

C305256

Grouped product items
SKU	Size	Availability	Price
C305256-1mg	1mg	In stock	$51.90
C305256-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$109.90
C305256-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$179.90
C305256-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$309.90
C305256-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$459.90

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Basic Description

Synonyms	Cucurbitacin E\|18444-66-1\|alpha-Elaterin\|alpha-Elaterine\|ELATERIN, ALPHA\|Cucurbitacine E\|.alpha.-Elaterin\|.alpha.-Elaterine\|NSC-106399\|CHEBI:3944\|V8A45XYI21\|[(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,1
Specifications & Purity	>99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Cucurbitacin E is a natural compound which from the climbing stem of Cucumic melo L. Cucurbitacin E significantly suppresses the activity of the cyclin B1/CDC2 complex. Cucurbitacin E has been used as a cofilin inhibitor, It is also used as a F-actin stabilizer to prevent membrane-associated periodic skeleton (MPS) loss and protect from axonal fragmentation.

Names and Identifiers

IUPAC Name	[(E,6R)-6-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
INCHI	InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1
InChi Key	NDYMQXYDSVBNLL-MUYMLXPFSA-N
Canonical SMILES	CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3C=C(C(=O)C4(C)C)O)C)C)C)O)O
Isomeric SMILES	CC(=O)OC(C)(C)/C=C/C(=O)[C@@](C)([C@H]1[C@@H](C[C@@]2([C@@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3C=C(C(=O)C4(C)C)O)C)C)C)O)O
PubChem CID	5281319
Molecular Weight	556.69

Certificates

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9 results found

Lot Number	Certificate Type	Date	Item
H2405465	Certificate of Analysis	Jun 19, 2024	C305256
H2405466	Certificate of Analysis	Jun 19, 2024	C305256
H2405467	Certificate of Analysis	Jun 19, 2024	C305256
H2405499	Certificate of Analysis	Jun 19, 2024	C305256
H2405500	Certificate of Analysis	Jun 19, 2024	C305256
H2405501	Certificate of Analysis	Jun 19, 2024	C305256
D2108149	Certificate of Analysis	Jan 15, 2023	C305256
D2108151	Certificate of Analysis	Jan 15, 2023	C305256
D2108152	Certificate of Analysis	Jan 15, 2023	C305256

Solubility

DMSO: 15 mg/mL, clear

Specific Rotation[α]

[α]/D -60 to -75°, c = 0.7 (CDCl3)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.

Solution Calculators

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Basic Description