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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C346200-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $38.90 | |
C346200-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $61.90 | |
C346200-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $123.90 | |
C346200-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $209.90 | |
C346200-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $334.90 |
an sEH inhibitor and selective PPARα activator
Synonyms | CUDA|479413-68-8|12-(cyclohexylcarbamoylamino)dodecanoic acid|12-[(CYCLOHEXYLCARBAMOYL)AMINO]DODECANOIC ACID|12-(3-Cyclohexylureido)dodecanoic acid|SCHEMBL1066578|CHEMBL3661356|DTXSID60629291|CHEBI:181802|BDBM129262|HMS3650M07|AKOS040732882|MS-25204|HY-12 |
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Specifications & Purity | 95% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | CUDA is an inhibitor of soluble epoxide hydrolase (sEH, IC|50|= 11.1 nM in mice). Studies have shown that 10 μM of CUDA can block the conversion of 14,15-EET to 14,15-DHET by 94% in COS-7 cells. CUDA selectively activates peroxisome proliferator-activated receptor α (PPARα) 8-fold at a concentration of 10 μM with no affect on PPARδ or PPARγ.CUDA may be valuable for the study of cardiovascular diseases. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 12-(cyclohexylcarbamoylamino)dodecanoic acid |
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INCHI | InChI=1S/C19H36N2O3/c22-18(23)15-11-6-4-2-1-3-5-7-12-16-20-19(24)21-17-13-9-8-10-14-17/h17H,1-16H2,(H,22,23)(H2,20,21,24) |
InChi Key | HPTJABJPZMULFH-UHFFFAOYSA-N |
Canonical SMILES | C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O |
Isomeric SMILES | C1CCC(CC1)NC(=O)NCCCCCCCCCCCC(=O)O |
PubChem CID | 22978774 |
Molecular Weight | 340.50 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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F2420123 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420124 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420125 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420126 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420127 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420128 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420129 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420130 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420131 | Certificate of Analysis | Feb 28, 2024 | C346200 |
F2420507 | Certificate of Analysis | Feb 28, 2024 | C346200 |