JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

Home
Applications
Targets
Kinases
CAMK:Calcium/calmodulin-dependent protein kinases
CX-5011 , CAS No.C609626, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase

CX-5011 , CAS No.C609626, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase

Item Number

C609626

Grouped product items
SKU	Size	Availability	Price	Qty
C609626-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$600.90
C609626-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

Basic Description

Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	5-(3-ethynylanilino)pyrimido[4,5-c]quinoline-8-carboxylate
INCHI	InChI=1S/C20H12N4O2/c1-2-12-4-3-5-14(8-12)23-19-18-16(10-21-11-22-18)15-7-6-13(20(25)26)9-17(15)24-19/h1,3-11H,(H,23,24)(H,25,26)/p-1
InChi Key	HJGFPNFAFSFDNN-UHFFFAOYSA-M
Canonical SMILES	C#Cc1cccc(c1)Nc1nc2cc(ccc2c2c1ncnc2)C(=O)[O-]
Isomeric SMILES	C#CC1=CC(=CC=C1)NC2=NC3=C(C=CC(=C3)C(=O)[O-])C4=CN=CN=C42
PubChem CID	72200352

PubChem CID	72200352
BindingDB Ligand	92756

Enter Lot Number to search for COA:

1. Battistutta R, Cozza G, Pierre F, Papinutto E, Lolli G, Sarno S, O'Brien SE, Siddiqui-Jain A, Haddach M, Anderes K et al.. (2011) Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer.. Biochemistry, 50 (39): (8478-88). [PMID:21870818]

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.