CX 546 - ≥98%(HPLC), high purity , CAS No.215923-54-9, Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4

Item Number

C132833

• Synonyms: 215923-54-9|CX546|CX 546|CX-546|(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(piperidin-1-yl)methanone|2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone|BDP 17|GR 87|2,3-Dihydro-1,4-benzodioxin-7-yl-(1-piperidyl)methanone|BDP-17|PV6YEC8983|GR-87|(2,3-Dihy
• Specifications & Purity: Moligand™, ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: CX546 has antipsychotic functionality and has the potential to treat schizophrenia. It improves the defects associated with the prepulse inhibition (PPI) and latent inhibition (LI) in mice lacking metabotropic glutamate receptor type 5 (mGluR5). Additiona
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: ALLOSTERIC MODULATOR
• Mechanism of action: Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4

Product Description

Product Introduction

CX546, a benzoylpiperidine derivative ampakine is an analog of CX516.

Application

CX546 has been used as positive allosteric modulator for the glutamatergic receptor α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) in mice.