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CXCL12β, CAS No.rp173768, Agonist of CXCR4

  • Moligand™
Features and benefits
    Item Number
    rp173768
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp173768-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp173768-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90
    View related series
    CXCR4 Agonist

    Basic Description

    Product NameCXCL12β, CAS No.rp173768
    SynonymsSDF-1β;stromal cell-derived factor-1 (SDF-1);stromal cell-derived factor-1β
    GradeMoligand™
    Action TypeAGONIST
    Mechanism of actionAgonist of CXCR4

    Associated Targets

    CXCR4 Tclin C-X-C chemokine receptor type 4 0 Activities

    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

    Product Specifications

    CASrp173768

    Certificates

    Certificate of Analysis(COA)

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    Genetic information

    Alternate NamesSDF-1β;stromal cell-derived factor-1 (SDF-1);stromal cell-derived factor-1β
    Reference
    • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
    • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
    • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
    • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
    • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
    • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
    • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
    • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
    • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
    • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

    Related Documents

    References

    1. Sierro F, Biben C, Martínez-Muñoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martínez-A C, Mackay CR, Mackay F.  (2007)  Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7..  Proc Natl Acad Sci USA,  104  (37): (14759-64).  [PMID:17804806]
    2. Nagasawa T, Hirota S, Tachibana K, Takakura N, Nishikawa S, Kitamura Y, Yoshida N, Kikutani H, Kishimoto T.  (1996)  Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1..  Nature,  382  (6592): (635-8).  [PMID:8757135]
    3. Tachibana K, Hirota S, Iizasa H, Yoshida H, Kawabata K, Kataoka Y, Kitamura Y, Matsushima K, Yoshida N, Nishikawa S et al..  (1998)  The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract..  Nature,  393  (6685): (591-4).  [PMID:9634237]
    4. Zou YR, Kottmann AH, Kuroda M, Taniuchi I, Littman DR.  (1998)  Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development..  Nature,  393  (6685): (595-9).  [PMID:9634238]

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