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CXCL17, CAS No.rp173782, Agonist of GPR35

  • Moligand™
Features and benefits
    Item Number
    rp173782
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp173782-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp173782-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90
    View related series
    GPR35 Agonist

    Basic Description

    Product NameCXCL17, CAS No.rp173782
    SynonymsC-X-C motif chemokine 17;dendritic cell and monocyte chemokine-like protein
    GradeMoligand™
    Action TypeAGONIST
    Mechanism of actionAgonist of GPR35

    Associated Targets

    GPR35 Tchem G-protein coupled receptor 35 0 Activities

    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

    Product Specifications

    CASrp173782

    Certificates

    Certificate of Analysis(COA)

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    Genetic information

    Alternate NamesC-X-C motif chemokine 17;dendritic cell and monocyte chemokine-like protein
    Reference
    • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
    • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
    • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
    • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
    • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
    • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
    • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
    • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
    • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
    • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

    Related Documents

    References

    1. Burkhardt AM, Tai KP, Flores-Guiterrez JP, Vilches-Cisneros N, Kamdar K, Barbosa-Quintana O, Valle-Rios R, Hevezi PA, Zuñiga J, Selman M et al..  (2012)  CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity..  J Immunol,  188  (12): (6399-406).  [PMID:22611239]
    2. Lee WY, Wang CJ, Lin TY, Hsiao CL, Luo CW.  (2013)  CXCL17, an orphan chemokine, acts as a novel angiogenic and anti-inflammatory factor..  Am J Physiol Endocrinol Metab,  304  (1): (E32-40).  [PMID:23115081]
    3. Burkhardt AM, Maravillas-Montero JL, Carnevale CD, Vilches-Cisneros N, Flores JP, Hevezi PA, Zlotnik A.  (2014)  CXCL17 is a major chemotactic factor for lung macrophages..  J Immunol,  193  (3): (1468-74).  [PMID:24973458]
    4. Maravillas-Montero JL, Burkhardt AM, Hevezi PA, Carnevale CD, Smit MJ, Zlotnik A.  (2015)  Cutting edge: GPR35/CXCR8 is the receptor of the mucosal chemokine CXCL17..  J Immunol,  194  (1): (29-33).  [PMID:25411203]

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