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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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C339850-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $68.90 | |
C339850-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
C339850-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $159.90 | |
C339850-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $288.90 | |
C339850-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $519.90 |
a cyclic dipeptide containing histidine and proline
Synonyms | Cyclo(his-pro)|Cyclo(-His-Pro)|53109-32-3|Cyclo(L-His-L-Pro)|MLS000028694|Q10817UXVT|CYCLO-(L-HISTIDINE-L-PROLINE) INHIBITOR|SMR000058881|UNII-Q10817UXVT|L-His-L-Pro-DKP|1w1t|Opera_ID_1205|L,L-cyclo(histidylprolyl)|Cyclo(histidyl-proline);Histidylproline |
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Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone. Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses. Application:
Cyclo(L-His-L-Pro) is a versatile molecule and it finds application in biochemical and metabolomics research.
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IUPAC Name | (3S,8aS)-3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione |
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INCHI | InChI=1S/C11H14N4O2/c16-10-9-2-1-3-15(9)11(17)8(14-10)4-7-5-12-6-13-7/h5-6,8-9H,1-4H2,(H,12,13)(H,14,16)/t8-,9-/m0/s1 |
InChi Key | NAKUGCPAQTUSBE-IUCAKERBSA-N |
Canonical SMILES | C1CC2C(=O)NC(C(=O)N2C1)CC3=CN=CN3 |
Isomeric SMILES | C1C[C@H]2C(=O)N[C@H](C(=O)N2C1)CC3=CN=CN3 |
WGK Germany | 3 |
PubChem CID | 449094 |
Molecular Weight | 234.26 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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E2430172 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430173 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430174 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430180 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430184 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430188 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430189 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430190 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430195 | Certificate of Analysis | Apr 22, 2024 | C339850 |
E2430196 | Certificate of Analysis | Apr 22, 2024 | C339850 |
Solubility | Soluble in water (Miscible). |
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Refractive Index | n20D~1.63 (Predicted) |
Specific Rotation[α] | +54.8° to +55.5°(c=10 in 0.2 ml 6N NH4OH/100 ml H2O) |
Boil Point(°C) | 744.8° C at 760 mmHg |
Melt Point(°C) | 165-170° C |
WGK Germany | 3 |
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