We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is biorenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks".Click herefor more information.Cyrene is a biobased dipolar, aprotic alternative to common solvents that are of environmental concern. Cyrene is an alternative for many solvents classified by REACH as Substances of Very High Concern (SVHC), such as N-Methylpyrorrolidone (NMP) and Dimethylformamide (DMF).In testing, Cyrene has shown to behave similarly to NMP with minimal loss in performance in heteroatom alkylation and nucleophilic fluorination reactions.Cyrene has been demonstrated to exceed NMP′s dispersive ability for graphene solutions. Graphene concentrations in Cyrene are an order of magnitude greater than with NMP due to its optimum polarity and high viscosity, creating larger and less defective graphene flakes.
1.Kirsty L Wilson,Alan R Kennedy,Jane Murray,Ben Greatrex,Craig Jamieson,Allan J B Watson. (2016-11-11) Scope and limitations of a DMF bio-alternative within Sonogashira cross-coupling and Cacchi-type annulation.. Beilstein journal of organic chemistry, 12 (2005-2011). [PMID:27829904]
2.Amani Alhifthi,Benjamin L Harris,Lars Goerigk,Jonathan M White,Spencer J Williams. (2017-11-25) Structure-reactivity correlations of the abnormal Beckmann reaction of dihydrolevoglucosenone oxime.. Organic & biomolecular chemistry, 15 ((47)):(10105-10115). [PMID:29170781]
3.Kirsty L Wilson,Jane Murray,Craig Jamieson,Allan J B Watson. (2018-04-10) Cyrene as a bio-based solvent for HATU mediated amide coupling.. Organic & biomolecular chemistry, 16 ((16)):(2851-2854). [PMID:29630081]
4.Jason E Camp. (2018-07-26) Bio-available Solvent Cyrene: Synthesis, Derivatization, and Applications.. ChemSusChem, 11 ((18)):(3048-3055). [PMID:30044553]
5.Kewen Pan,Yangyang Fan,Ting Leng,Jiashen Li,Zhiying Xin,Jiawei Zhang,Ling Hao,John Gallop,Kostya S Novoselov,Zhirun Hu. (2018-12-07) Sustainable production of highly conductive multilayer graphene ink for wireless connectivity and IoT applications.. Nature communications, 9 ((1)):(5197-5197). [PMID:30518870]
6.James Sherwood,Mario De bruyn,Andri Constantinou,Laurianne Moity,C Rob McElroy,Thomas J Farmer,Tony Duncan,Warwick Raverty,Andrew J Hunt,James H Clark. (2014-07-10) Dihydrolevoglucosenone (Cyrene) as a bio-based alternative for dipolar aprotic solvents.. Chemical communications (Cambridge, England), 50 ((68)):(9650-9652). [PMID:25007289]
7.Christian Grune,Jana Thamm,Oliver Werz,Dagmar Fischer. (2020-12-05) Cyrene™ as an Alternative Sustainable Solvent for the Preparation of Poly(lactic-co-glycolic acid) Nanoparticles.. Journal of pharmaceutical sciences, 110 ((2)):(959-964). [PMID:33275992]
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