Cytochalasin J - 95%, high purity , CAS No.53760-20-6

Item Number

C329406

Grouped product items
SKU	Size	Availability	Price	Qty
C329406-1mg	1mg	In stock	$110.90
C329406-5mg	5mg	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$495.90

a cell-permeable fungal toxin used in actin polymerization studies and cytological research

Basic Description

Synonyms	Cytochalasin j\|53760-20-6\|(1R,2R,3Z,5R,7S,9Z,11R,12S,14S,15R,16S)-16-benzyl-2,5,12-trihydroxy-5,7,14-trimethyl-13-methylidene-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-18-one
Specifications & Purity	95%
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Cytochalasin J is used in actin polymerization studies. Cytochalasins are potent mycotoxins which bind to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. These fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. Cytochalasin J is the deacetyl analogue of cytochalasin H and exhibits similar, though less potent, antibacterial, antifungal, nematocidal and antitumor activities. Application： Cytochalasin J is a cell-permeable fungal toxin used in actin polymerization studies and cytological research

Names and Identifiers

Pubchem Sid	488202606
IUPAC Name	(1R,2R,3Z,5R,7S,9Z,11R,12S,14S,15R,16S)-16-benzyl-2,5,12-trihydroxy-5,7,14-trimethyl-13-methylidene-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-18-one
INCHI	InChI=1S/C28H37NO4/c1-17-9-8-12-21-25(31)19(3)18(2)24-22(15-20-10-6-5-7-11-20)29-26(32)28(21,24)23(30)13-14-27(4,33)16-17/h5-8,10-14,17-18,21-25,30-31,33H,3,9,15-16H2,1-2,4H3,(H,29,32)/b12-8-,14-13-/t17-,18+,21-,22-,23+,24-,25+,27-,28+/m0/s1
InChi Key	UKQNIEMKORIOQM-RVVPKKHWSA-N
Canonical SMILES	CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1)(C)O)O)C(=O)NC3CC4=CC=CC=C4)C)O
Isomeric SMILES	C[C@H]1C/C=C\[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C\[C@](C1)(C)O)O)C(=O)N[C@H]3CC4=CC=CC=C4)C)O
WGK Germany	3
PubChem CID	102239810
Molecular Weight	451.6

Certificates

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4 results found

Lot Number	Certificate Type	Date	Item
C2323621	Certificate of Analysis	Dec 15, 2022	C329406
C2323628	Certificate of Analysis	Dec 15, 2022	C329406
C2323634	Certificate of Analysis	Dec 15, 2022	C329406
C2323657	Certificate of Analysis	Dec 15, 2022	C329406

Solubility

Soluble in ethanol, methanol, DMF, DMSO, and water (poorly).

Sensitivity

Light sensitive

Refractive Index

n20D1.61 (Predicted)

Boil Point(°C)

679.51° C at 760 mmHg (Predicted)

Melt Point(°C)

137-139° C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H351:Suspected of causing cancer H300:Fatal if swallowed H310:Fatal in contact with skin H330:Fatal if inhaled
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P316:Get emergency medical help immediately.
WGK Germany	3

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Basic Description