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D-AP4 - ≥98%(HPLC), high purity , CAS No.78739-01-2, Agonist of mGlu 8 receptor
Broad spectrum glutamatergic antagonist
Basic Description Synonyms D-AP4|78739-01-2|(2R)-2-amino-4-phosphonobutanoic acid|(R)-2-Amino-4-phosphonobutanoic acid|Butanoic acid, 2-amino-4-phosphono-, (2R)-|D27J5G57JL|D-2-amino-4-phosphonobutanoic acid|d(-)-2-amino-4-phosphonobutyric acid|2-Amino-4-phosphonobutyric acid, (R)- Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Broad spectrum excitatory amino acid receptor antagonist. Also agonist at the quisqualate-sensitized AP6 site in hippocampus where it is less potent than L-AP4.DL MixtureandL-isomeralso available. Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of mGlu 8 receptor
Names and Identifiers IUPAC Name (2R)-2-amino-4-phosphonobutanoic acid INCHI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m1/s1 InChi Key DDOQBQRIEWHWBT-GSVOUGTGSA-N Canonical SMILES C(CP(=O)(O)O)C(C(=O)O)N Isomeric SMILES C(CP(=O)(O)O)[C@H](C(=O)O)N PubChem CID 1550579 Molecular Weight 183.1
Chemical and Physical Properties Solubility Solvent:1eq. NaOH, Max Conc. mg/mL: None, Max Conc. mM: 100
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