Skip to the beginning of the images gallery

D-Biotin N-Succinimidyl Ester - 98%, high purity , CAS No.35013-72-0

≥98%

CAS#: 35013-72-0
Formula: C₁₄H₁₉N₃O₅S
Molecular Weight: 341.38
Beilstein Registry Number: 4720781
MDL number: MFCD00078531
PubChem CID: 6710714
PubChem SID: 488195856

Item Number

N103916

Grouped product items
SKU	Size	Availability	Price
N103916-10mg	10mg	In stock	$9.90
N103916-50mg	50mg	In stock	$32.90
N103916-250mg	250mg	In stock	$125.90
N103916-1g	1g	In stock	$385.90
N103916-5g	5g	In stock	$1,735.90
N103916-25g	25g	In stock	$7,810.90

Discover D-Biotin N-Succinimidyl Ester by Aladdin Scientific in 98% for only $9.90. Available - in Ligands at Aladdin Scientific. Activated biotin derivative for labeling primary and secondary amines Tags: Five-Membered Heterocyclic Compounds, Imide.

View related series

Five-Membered Heterocyclic Compounds Imide

Basic Description

Synonyms	35013-72-0\|Biotin-NHS\|(+)-Biotin N-hydroxysuccinimide ester\|NHS-Biotin\|Biotin NHS\|Biotin N-Hydroxysuccinimide Ester\|Biotin-NHS ester\|N-Hydroxysuccinimidobiotin\|N-Succinimidyl D-biotinate\|(+)-Biotin-NHS ester\|Biotin-OSu\|2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,
Specifications & Purity	98%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	It is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides. It may be used in the biotinylation of proteins and peptides. Typically coupled to primary amine in the pH range 6.5-8.5.

Names and Identifiers

Pubchem Sid	488195856
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
INCHI	InChI=1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)/t8-,9-,13-/m0/s1
InChi Key	YMXHPSHLTSZXKH-RVBZMBCESA-N
Canonical SMILES	C1CC(=O)N(C1=O)OC(=O)CCCCC2C3C(CS2)NC(=O)N3
Isomeric SMILES	C1CC(=O)N(C1=O)OC(=O)CCCC[C@H]2[C@@H]3[C@H](CS2)NC(=O)N3
WGK Germany	3
PubChem CID	6710714
Molecular Weight	341.38
Beilstein	4720781
Reaxy-Rn	4720781

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

11 results found

Lot Number	Certificate Type	Date	Item
E2408208	Certificate of Analysis	Apr 01, 2024	N103916
E2408209	Certificate of Analysis	Apr 01, 2024	N103916
B2318122	Certificate of Analysis	Nov 28, 2022	N103916
B2318141	Certificate of Analysis	Nov 28, 2022	N103916
B2318142	Certificate of Analysis	Nov 28, 2022	N103916
B2318143	Certificate of Analysis	Nov 28, 2022	N103916
B2318211	Certificate of Analysis	Nov 28, 2022	N103916
B2318212	Certificate of Analysis	Nov 28, 2022	N103916
B2318218	Certificate of Analysis	Nov 28, 2022	N103916
H2427065	Certificate of Analysis	Nov 28, 2022	N103916
A2221079	Certificate of Analysis	May 18, 2021	N103916

Chemical and Physical Properties

Solubility	Soluble in Dimethylformamide 50 mg/mL (Stable for at least one month in dry DMF). Soluble in Dimethyl sulfoxide(DMSO).
Sensitivity	Moisture & Heat & Air Sensitive
Melt Point(°C)	140°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	4720781

References

1. Tabdanov ED et al.. (2018) Bimodal sensing of guidance cues in mechanically distinct microenvironments.. Nat Commun, 9 (4891). [PMID:30459308]
2. Tabdanov ED et al.. (2018) Microtubule-Actomyosin Mechanical Cooperation during Contact Guidance Sensing.. Cell Rep, 25 (2): (328-338.e5). [PMID:30304674]
3. A R Hayward,J Clarke,M Cosyns. (1990-09-01) V beta 5 and V beta 8 memory T cells in adults and infancy: co-ordinated increase in response to early antigen stimulus.. Clinical and experimental immunology, 81 ((3)): (475-478). [PMID:2144485]
4. W J Mayet,M Bachmann,K Pfeifer,H C Schröder,W E Müller,W Gudat,G W Korting,K H Meyer zum Büschenfelde. (1988-10-01) A monoclonal Ro-antibody and the serum of a Ro-positive patient with subacute cutaneous lupus erythematosus (SCLE) react with basal layers of human epidermis.. European journal of clinical investigation, 18 ((5)): (465-471). [PMID:3147897]
5. E U Bağriaçik,J R Klein. (2000-06-08) The thyrotropin (thyroid-stimulating hormone) receptor is expressed on murine dendritic cells and on a subset of CD45RBhigh lymph node T cells: functional role for thyroid-stimulating hormone during immune activation.. Journal of immunology (Baltimore, Md. : 1950), 164 ((12)): (6158-6165). [PMID:10843665]
6. L S Ayong,C B Tume,F E Wembe,G Simo,T Asonganyi,G Lando,J L Ngu. (2005-02-26) Development and evaluation of an antigen detection dipstick assay for the diagnosis of human onchocerciasis.. Tropical medicine & international health : TM & IH, 10 ((3)): (228-233). [PMID:15730506]
7. Yijun Tang,Ray Mernaugh,Xiangqun Zeng. (2006-03-16) Nonregeneration protocol for surface plasmon resonance: study of high-affinity interaction with high-density biosensors.. Analytical chemistry, 78 ((6)): (1841-1848). [PMID:16536419]
8. C A Yoder,J K Graham,L A Miller. (2006-07-13) Molecular effects of nicarbazin on avian reproduction.. Poultry science, 85 ((7)): (1285-1293). [PMID:16830870]
9. Denise Dorvignit,Julio L Palacios,Maylin Merino,Tays Hernández,Katya Sosa,Angel Casaco,Alejandro López-Requena,Cristina Mateo de Acosta. (2012-06-01) Expression and biological characterization of an anti-CD20 biosimilar candidate antibody: a case study.. mAbs, 4 ((4)): (488-496). [PMID:22647435]
10. Troels R Kjaer,Annette G Hansen,Uffe B S Sørensen,Anne T Holm,Grith L Sørensen,Jens C Jensenius,Steffen Thiel. (2012-11-28) M-ficolin binds selectively to the capsular polysaccharides of Streptococcus pneumoniae serotypes 19B and 19C and of a Streptococcus mitis strain.. Infection and immunity, 81 ((2)): (452-459). [PMID:23184524]
11. María de los Angeles Serrano,Melchor Emilio Luque,Sara Serafina Sánchez. (2013-07-31) Xepac protein and IP3/Ca2+ pathway implication during Xenopus laevis vitellogenesis.. Zygote (Cambridge, England), 23 ((1)): (99-110). [PMID:23890344]
12. Susanne Gjørup Sækmose,Anders Schlosser,René Holst,Sofie Lock Johansson,Helle Wulf-Johansson,Ida Tornøe,Jørgen Vestbo,Kirsten Ohm Kyvik,Torben Barington,Uffe Holmskov,Grith Lykke Sørensen. (2013-12-11) Enzyme-linked immunosorbent assay characterization of basal variation and heritability of systemic microfibrillar-associated protein 4.. PloS one, 8 ((12)): (e82383-e82383). [PMID:24324779]
13. Maria de Lourdes Muñoz,Gustavo Limón-Camacho,Rosalinda Tovar,Alvaro Diaz-Badillo,Guillermo Mendoza-Hernández,William C Black. (2013-12-11) Proteomic identification of dengue virus binding proteins in Aedes aegypti mosquitoes and Aedes albopictus cells.. BioMed research international, 2013 (875958-875958). [PMID:24324976]
14. Helle Wulf-Johansson,Sofie Lock Johansson,Anders Schlosser,Anne Trommelholt Holm,Lars Melholt Rasmussen,Hans Mickley,Axel C P Diederichsen,Henrik Munkholm,Tina Svenstrup Poulsen,Ida Tornøe,Vicki Nielsen,Niels Marcussen,Jørgen Vestbo,Susanne Gjørup Sækmose,Uffe Holmskov,Grith Lykke Sorensen. (2013-12-19) Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions.. PloS one, 8 ((12)): (e82243-e82243). [PMID:24349233]
15. Anne Rosbjerg,Lea Munthe-Fog,Peter Garred,Mikkel-Ole Skjoedt. (2014-04-01) Heterocomplex formation between MBL/ficolin/CL-11-associated serine protease-1 and -3 and MBL/ficolin/CL-11-associated protein-1.. Journal of immunology (Baltimore, Md. : 1950), 192 ((9)): (4352-4360). [PMID:24683193]
16. Zhihui Peng,Min Ling,Yi Ning,Le Deng. (2014-04-26) Rapid fluorescent detection of Escherichia coli K88 based on DNA aptamer library as direct and specific reporter combined with immuno-magnetic separation.. Journal of fluorescence, 24 ((4)): (1159-1168). [PMID:24763818]
17. Matthew S Graus,Carolyn Pehlke,Michael J Wester,Lisa B Davidson,Stanly L Steinberg,Aaron K Neumann. (2014-05-31) A new tool to quantify receptor recruitment to cell contact sites during host-pathogen interaction.. PLoS computational biology, 10 ((5)): (e1003639-e1003639). [PMID:24874253]
18. Zahra Kadri,Carine Lefevre,Olivier Goupille,Tipparat Penglong,Marine Granger-Locatelli,Suthat Fucharoen,Leila Maouche-Chretien,Philippe Leboulch,Stany Chretien. (2015-12-19) Erythropoietin and IGF-1 signaling synchronize cell proliferation and maturation during erythropoiesis.. Genes & development, 29 ((24)): (2603-2616). [PMID:26680303]
19. Jia Lin,Michael J Wester,Matthew S Graus,Keith A Lidke,Aaron K Neumann. (2016-01-23) Nanoscopic cell-wall architecture of an immunogenic ligand in Candida albicans during antifungal drug treatment.. Molecular biology of the cell, 27 ((6)): (1002-1014). [PMID:26792838]
20. Concepción Palomo,Vicente Mas,Laurent Detalle,Erik Depla,Olga Cano,Mónica Vázquez,Catelijne Stortelers,José A Melero. (2016-08-24) Trivalency of a Nanobody Specific for the Human Respiratory Syncytial Virus Fusion Glycoprotein Drastically Enhances Virus Neutralization and Impacts Escape Mutant Selection.. Antimicrobial agents and chemotherapy, 60 ((11)): (6498-6509). [PMID:27550346]
21. Aziza P Manceur,Wei Zou,Anne Marcil,Eric Paquet,Christine Gadoury,Bozena Jaentschke,Xuguang Li,Emma Petiot,Yves Durocher,Jason Baardsnes,Manuel Rosa-Calatrava,Sven Ansorge,Amine A Kamen. (2017-07-01) Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza.. PloS one, 12 ((6)): (e0180314-e0180314). [PMID:28662134]
22. Ying-Xia Tan,Hao Cui,Lu-Ming Wan,Feng Gong,Xiao Zhang,Israel Vlodavsky,Jin-Ping Li. (2018-02-23) Overexpression of heparanase in mice promoted megakaryopoiesis.. Glycobiology, 28 ((5)): (269-275). [PMID:29471321]
23. Dong Guk Cho,Haneul Yoo,Haein Lee,Yeol Kyo Choi,Minju Lee,Dong June Ahn,Seunghun Hong. (2018-05-12) High-Speed Lateral Flow Strategy for a Fast Biosensing with an Improved Selectivity and Binding Affinity.. Sensors (Basel, Switzerland), 18 ((5)): [PMID:29748509]
24. Yongjae Jo,Junhwan Kwon,Moonseok Kim,Wonshik Choi,Myunghwan Choi. (2018-11-06) Microsphere-based interferometric optical probe.. Nature communications, 9 ((1)): (4577-4577). [PMID:30385746]
25. Jes Sanddal Lindholt,Mathilde Madsen,Katrine Lindequist Kirketerp-Møller,Anders Schlosser,Katrine Lawaetz Kristensen,Carsten Behr Andersen,Grith Lykke Sorensen. (2019-12-01) High plasma microfibrillar-associated protein 4 is associated with reduced surgical repair in abdominal aortic aneurysms.. Journal of vascular surgery, 71 ((6)): (1921-1929). [PMID:31784280]
26. Niko Amin-Wetzel,Lisa Neidhardt,Yahui Yan,Matthias P Mayer,David Ron. (2019-12-25) Unstructured regions in IRE1α specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR.. eLife, 8 [PMID:31873072]
27. Erdem D Tabdanov,Alexander S Zhovmer,Vikram Puram,Paolo P Provenzano. (2020-08-01) Engineering Elastic Nano- and Micro-Patterns and Textures for Directed Cell Motility.. STAR protocols, 1 ((1)): [PMID:32734278]
28. Chatterjee, et al.. (2021) Direct kinetic fingerprinting and digital counting of single protein molecules.. Proceedings of the National Academy of Sciences of the USA, 117 (22815-22822). [PMID:32868420]
29. Rong Yan,Xinxin Ge,Ningbo Pang,Honglei Ye,Liuxia Yuan,Bin Cheng,Kangxi Zhou,Mengnan Yang,Yueyue Sun,Suqin Zhang,Zhongren Ding,Jincai Luo,Changgeng Ruan,Kesheng Dai. (2021-10-18) Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression.. Cell death & disease, 12 ((11)): (955-955). [PMID:34657146]
30. M J Kim,H J Kim,J M Kim,B Kim,S H Han,G S Cha. (1995-11-01) Homogeneous assays for riboflavin mediated by the interaction between enzyme-biotin and avidin-riboflavin conjugates.. Analytical biochemistry, 231 ((2)): (400-406). [PMID:8594992]
31. S B Laursen,J E Hedemand,O L Nielsen,S Thiel,C Koch,J C Jensenius. (1998-10-10) Serum levels, ontogeny and heritability of chicken mannan-binding lectin (MBL).. Immunology, 94 ((4)): (587-593). [PMID:9767449]
32. Attila Lehotzky,Judit Oláh,Sándor Szunyogh,Adél Szabó,Tímea Berki,Judit Ovádi. (2014-12-03) Zinc-induced structural changes of the disordered tppp/p25 inhibits its degradation by the proteasome.. Biochimica et biophysica acta, 1852 ((1)): (83-91). [PMID:25445539]
33. Cecilie Bo Hansen,Dorottya Csuka,Lea Munthe-Fog,Lilian Varga,Henriette Farkas,Karin Møller Hansen,Claus Koch,Karsten Skjødt,Peter Garred,Mikkel-Ole Skjoedt. (2015-09-16) The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema.. Journal of immunology (Baltimore, Md. : 1950), 195 ((8)): (3596-3604). [PMID:26371246]
34. Casper Bo Jensen,Charles Pyke,Morten Grønbech Rasch,Anders Bjorholm Dahl,Lotte Bjerre Knudsen,Anna Secher. (2017-11-03) Characterization of the Glucagonlike Peptide-1 Receptor in Male Mouse Brain Using a Novel Antibody and In Situ Hybridization.. Endocrinology, 159 ((2)): (665-675). [PMID:29095968]
35. Niko Amin-Wetzel,Reuben A Saunders,Maarten J Kamphuis,Claudia Rato,Steffen Preissler,Heather P Harding,David Ron. (2017-12-05) A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response.. Cell, 171 ((7)): (1625-1637). [PMID:29198525]
36. A A Panina,I G Dementieva,T K Aliev,V A Toporova,D S Balabashin,M N Bokov,L P Pozdnyakova,O B Shchemchukova,D A Dolgikh,P G Sveshnikov,M P Kirpichnikov. (2018-01-18) Recombinant Antibodies to the Ebola Virus Glycoprotein.. Acta naturae, 9 ((4)): (84-91). [PMID:29340221]
37. Ahmed Metwali,Peter S Thorne,M Nedim Ince,Nervana Metwali,Sarah Winckler,Xiaoqun Guan,Sonay Beyatli,Jamie Truscott,Joseph F Urban,David E Elliott. (2018-07-20) Recirculating Immunocompetent Cells in Colitic Mice Intensify Their Lung Response to Bacterial Endotoxin.. Digestive diseases and sciences, 63 ((11)): (2930-2939). [PMID:30022451]
38. Hussein A Almehdar,Nawal Abd El-Baky,Abdulqader A Alhaider,Saud A Almuhaideb,Abdullah A Alhaider,Raed S Albiheyri,Vladimir N Uversky,Elrashdy M Redwan. (2019-02-07) Bacteriostatic and Bactericidal Activities of Camel Lactoferrins Against Salmonella enterica Serovar Typhi.. Probiotics and antimicrobial proteins, 12 ((1)): (18-31). [PMID:30723884]
39. Veronika Horkova,Ales Drobek,Daniel Mueller,Celine Gubser,Veronika Niederlova,Lena Wyss,Carolyn G King,Dietmar Zehn,Ondrej Stepanek. (2020-02-06) Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8\xa0T Cells.. Cell reports, 30 ((5)): (1504-1514). [PMID:32023465]
40. Marcus James Robinson,Zhoujie Ding,Catherine Pitt,Erica Janet Brodie,Isaak Quast,David Mathew Tarlinton,Dimitra Zotos. (2020-02-06) The Amount of BCL6 in B Cells Shortly after Antigen Engagement Determines Their Representation in Subsequent Germinal Centers.. Cell reports, 30 ((5)): (1530-1541). [PMID:32023467]
41. Kristóf G Kovács,Bernadett Mácsik-Valent,János Matkó,Zsuzsa Bajtay,Anna Erdei. (2021-04-20) Revisiting the Coreceptor Function of Complement Receptor Type 2 (CR2, CD21); Coengagement With the B-Cell Receptor Inhibits the Activation, Proliferation, and Antibody Production of Human B Cells.. Frontiers in immunology, 12 (620427-620427). [PMID:33868238]
42. Susanne Gjørup Sækmose,René Holst,Tine Lottenburger,Henriette Ytting,Hans Jørgen Nielsen,Peter Junker,Anders Schlosser,Grith Lykke Sorensen. (2021-05-27) Circadian, Week-to-Week, and Physical Exercise-Induced Variation of Serum Microfibrillar-Associated Protein 4.. Biomarker insights, 16 (11772719211016359-11772719211016359). [PMID:34035648]
43. Imre Gaspar,Frank Wippich,Anne Ephrussi. (2018-03-05) Terminal Deoxynucleotidyl Transferase Mediated Production of Labeled Probes for Single-molecule FISH or RNA Capture.. Bio-protocol, 8 ((5)): (e2750-e2750). [PMID:34179277]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.