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D,L-Buthionine-(S,R)-sulfoximine - 98%, high purity , CAS No.5072-26-4
Water soluble, potent, selective inhibitor of gamma-glutamyl cysteine synthase.
Basic Description Synonyms NCGC00093696-01 | DTXSID6044434 | LW4108Q0BV | B 2640 | BCP27775 | 2-Amino-4-(butylsulfonimidoyl)butanoicacid | NCGC00015148-04 | BSO | D,L-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) | EU-0100231 | LP00231 | NCGC00015148-05 | CHEBI:28714 | MFCD0 Specifications & Purity 98% Storage Temp Store at 2-8°C,Desiccated Shipped In Wet ice Product Description
DL-buthionine-SR-sulfoximine (BSO) is an amino acid analogue, which acts as an inhibitor of γ-glutamylcysteine synthetase. BSO increases the sensitivity of Trypanosoma cruzi to antiparasitic drugs, such as nifurtimox or benznidazole.
Names and Identifiers IUPAC Name 2-amino-4-(butylsulfonimidoyl)butanoic acid INCHI InChI=1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12) InChi Key KJQFBVYMGADDTQ-UHFFFAOYSA-N Canonical SMILES CCCCS(=N)(=O)CCC(C(=O)O)N Isomeric SMILES CCCCS(=N)(=O)CCC(C(=O)O)N PubChem CID 21157 Molecular Weight 222.31
Chemical and Physical Properties Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
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