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D-(+)-Trehalose dihydrate - from cassava starch,≥99%, high purity , CAS No.6138-23-4

12 Citations
  • ≥99%
  • from cassava starch
Item Number
T100010
Grouped product items
SKUSizeAvailabilityPrice Qty
T100010-25g
25g
In stock
$79.90
T100010-100g
100g
In stock
$199.90
T100010-500g
500g
In stock
$689.90
T100010-12×500g
12×500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$6,399.90
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Carbohydrates For Biochemical Research Natural glycosides

Basic Description

SynonymsTREHALOSE, DIHYDRATE | a-d-glucopyranosyl-a-d-glucopyranoside | DPVHGFAJLZWDOC-PVXXTIHASA-N | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol;dihydrate
Specifications & Purity≥99%, from cassava starch
Biochemical and Physiological MechanismsBiochem/physiol Actions：D-(+)-Trehalose shows anti-desiccant and cryopreservative activities. It acts as an osmolyte, and stress protectant and helps in the storage and transport of carbon. Trehalose is involved in the food, cosmetic, and pharmaceutical i
Storage TempArgon charged
Shipped InNormal
Product Description

Trehalose, Dihydrate, is an osmolyte, a chemical chaperone and inducer of autophagy, that has been reported to protect cells against numerous environmental stresses. This compound contains many properties that allow it to stabilize partially unfolded protein molecules and inhibit protein aggregation. These properties include a low chemical reactivity, high glass transition temperature, existence of numerous polymorphs, nonreducing nature, and high affinity for water molecules. Additionally, Trehalose has been noted to bind to expanded polyglutamines and stabilize partially unfolded polyglutamine-containing proteins.
An osmolyte, chemical chaperone, and inducer of autophagy.

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol;dihydrate
INCHI InChI=1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
InChi Key DPVHGFAJLZWDOC-PVXXTIHASA-N
Canonical SMILES [H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Isomeric SMILES C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)O)O.O.O
WGK Germany 2
PubChem CID 181978
Molecular Weight 378.33
Beilstein 5322018

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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30 results found

Lot NumberCertificate TypeDateItem
K2404664Certificate of AnalysisOct 23, 2024 T100010
K2404663Certificate of AnalysisOct 23, 2024 T100010
K2404662Certificate of AnalysisOct 23, 2024 T100010
K2404661Certificate of AnalysisOct 23, 2024 T100010
I2423551Certificate of AnalysisAug 26, 2024 T100010
I2423550Certificate of AnalysisAug 26, 2024 T100010
F2427531Certificate of AnalysisJun 07, 2024 T100010
F2427532Certificate of AnalysisJun 07, 2024 T100010
F2427533Certificate of AnalysisJun 07, 2024 T100010
F2427534Certificate of AnalysisJun 07, 2024 T100010
G2424009Certificate of AnalysisJun 07, 2024 T100010
B24261013Certificate of AnalysisFeb 01, 2024 T100010
B24261019Certificate of AnalysisFeb 01, 2024 T100010
B24261020Certificate of AnalysisFeb 01, 2024 T100010
H2308415Certificate of AnalysisMay 08, 2023 T100010
H2308421Certificate of AnalysisMay 08, 2023 T100010
H2308504Certificate of AnalysisMay 08, 2023 T100010
L2217047Certificate of AnalysisNov 29, 2022 T100010
L2217046Certificate of AnalysisNov 29, 2022 T100010
L22161034Certificate of AnalysisNov 29, 2022 T100010
L22161029Certificate of AnalysisNov 29, 2022 T100010
H2212467Certificate of AnalysisJun 09, 2022 T100010
G2223104Certificate of AnalysisJun 06, 2022 T100010
G2223069Certificate of AnalysisJun 06, 2022 T100010
G2223106Certificate of AnalysisJun 06, 2022 T100010
G2223103Certificate of AnalysisJun 06, 2022 T100010
D2213027Certificate of AnalysisMar 20, 2022 T100010
D2213028Certificate of AnalysisMar 20, 2022 T100010
D2213030Certificate of AnalysisMar 20, 2022 T100010
A2212225Certificate of AnalysisDec 15, 2021 T100010

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Chemical and Physical Properties

SolubilitySoluble in water (100 mg/ml), and hot alcohol.
SensitivityHygroscopic.
Specific Rotation[α]181 ° (C=7, H2O)
Melt Point(°C)97-99°C

Safety and Hazards(GHS)

WGK Germany 2
Merck Index 9580

Related Documents

 SDS

 Specification Sheet

Alternative Products

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    D-(+)-Trehalose dihydrate
    • 10mM in DMSO

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  2. D-(+)-Trehalose dihydrate - for cell culture,for insect cell culture,≥99%, used for , CAS No. 6138-23-4, by Aladdin Scientific
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FAQs and Articles

FAQ
Chelating Agents
Categories: Technical articles
Tags:
Drug development Protein purification Chelating agent Biological experiments Metal ions Nutrient uptake Heavy Metal removal Biochemical studies Enzyme activity Biological sample processing Metal ion analysis Microbial culture

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Hui Peng, Xin Wang, Fan Yang, Zhiyuan Liu, Haikuo Lei, Shuzhen Cui, Xuan Xie, Guofu Ma.  (2023)  Regulating solvation structure and inducing Zn (0 0 2) plane by a multifunctional electrolyte additive toward dendrite suppression and long-life zinc ion hybrid capacitors.  CHEMICAL ENGINEERING JOURNAL,  474  (1): (145864).  [PMID:18025162] [10.1016/j.cej.2023.145864]
2. Min Fan, Yan Li, Jingbo Chen, Yuxiang Lin, Shuxia Lai, Shirun Peng, Duo Lin, Jing Wang, Yudong Lu, Shangyuan Feng.  (2023)  Plasmonic internal standard-decorated nitrocellulose membranes for duplex detection of circulating tumor biomarkers.  SENSORS AND ACTUATORS B-CHEMICAL,  395  (134508).  [PMID:] [10.1016/j.snb.2023.134508]
3. Xin Du, Baohua Kong, Junjie He, Quanyu Zhang, Geer An, Tingting Zhang, Xiufang Xia.  (2023)  Cryoprotective effect of water-tailored trehalose-based natural deep eutectic solvents on frozen-thawed mirror carp (Cyprinus carpio L.) surimi.  FOOD CHEMISTRY,  426  (136633).  [PMID:37329788] [10.1016/j.foodchem.2023.136633]
4. Peng Yan, Xuewei Zheng, Shuang Liu, Yanhua Dong, Tao Fu, Zhongmin Tian, Yayan Wu.  (2023)  Colorimetric Sensor Array for Identification of Proteins and Classification of Metabolic Profiles under Various Osmolyte Conditions.  ACS Sensors,  8  (1): (133–140).  [PMID:36630575] [10.1021/acssensors.2c01847]
5. Liang Huang, Ziyu Shi, Daquan Li, Chenxing Jiang, Xuexue Wang, Mei Huang, Jing Wang, Bin Su.  (2023)  Hue-Recognition Strategy-Based Immunoassay Using Functionalized Dendritic Silica Colloids and Gold Nanoclusters for Point-of-Care Testing of C-Reactive Proteins.  ACS Applied Nano Materials,  6  (1): (86–95).  [PMID:] [10.1021/acsanm.2c03695]
6. Xiang Yu, Lin Zhu, Xiaohui Liang, Bochuan Yuan, Minshu Li, Shen Hu, Pingtian Ding, Lina Du, Junwang Guo, Yiguang Jin.  (2022)  A wearable gamma radiation-responsive granulocyte colony-stimulating factor microneedle system protecting against ionizing radiation-induced injury.  Acta Biomaterialia,  146  (197).  [PMID:35487423] [10.1016/j.actbio.2022.04.040]
7. Tingting Cui, Yaowen Wu, Fanghui Fan.  (2022)  Physicochemical properties and Strength analysis of vitreous encapsulated solids for the safe delivery of β-Carotene.  FOOD RESEARCH INTERNATIONAL,  151  (110877).  [PMID:34980407] [10.1016/j.foodres.2021.110877]
8. Zhang Lu, Li Yingying, Wei Fang, Liu Hang, Wang Yushuai, Zhao Weiman, Dong Zhiyong, Ma Tao, Wang Qingqing.  (2021)  Transdermal Delivery of Salmon Calcitonin Using a Dissolving Microneedle Array: Characterization, Stability, and In vivo Pharmacodynamics.  AAPS PHARMSCITECH,  22  (1): (1-9).  [PMID:33215299] [10.1208/s12249-020-01865-z]
9. Su Zixian, Zhao Guangying, Dou Wenchao.  (2020)  Determination of trace aflatoxin M1 (AFM1) residue in milk by an immunochromatographic assay based on (PEI/PSS)4 red silica nanoparticles.  MICROCHIMICA ACTA,  187  (12): (1-9).  [PMID:33201356] [10.1007/s00604-020-04636-6]
10. Xiang Yu, Minshu Li, Lin Zhu, Jingfei Li, Guoli Zhang, Rongzhen Fang, Zhihong Wu, Yiguang Jin.  (2020)  Amifostine-loaded armored dissolving microneedles for long-term prevention of ionizing radiation-induced injury.  Acta Biomaterialia,  112  (87).  [PMID:32450231] [10.1016/j.actbio.2020.05.025]
11. Shishan Fu, Song Miao, Xiaobin Ma, Tian Ding, Xingqian Ye, Donghong Liu.  (2019)  Inhibition of lactose crystallisation in the presence of galacto-oligosaccharide.  FOOD HYDROCOLLOIDS,  88  (127).  [PMID:] [10.1016/j.foodhyd.2018.09.043]
12. Guiju Xu, Shengju Liu, Jiaxi Peng, Wenping Lv, Ren’an Wu.  (2015)  Facile Synthesis of Gold@Graphitized Mesoporous Silica Nanocomposite and Its Surface-Assisted Laser Desorption/Ionization for Time-of-Flight Mass Spectroscopy.  ACS Applied Materials & Interfaces,  7  (3): (2032–2038).  [PMID:25552293] [10.1021/am507894y]

References

1. Hui Peng, Xin Wang, Fan Yang, Zhiyuan Liu, Haikuo Lei, Shuzhen Cui, Xuan Xie, Guofu Ma.  (2023)  Regulating solvation structure and inducing Zn (0 0 2) plane by a multifunctional electrolyte additive toward dendrite suppression and long-life zinc ion hybrid capacitors.  CHEMICAL ENGINEERING JOURNAL,  474  (1): (145864).  [PMID:18025162] [10.1016/j.cej.2023.145864]
2. Min Fan, Yan Li, Jingbo Chen, Yuxiang Lin, Shuxia Lai, Shirun Peng, Duo Lin, Jing Wang, Yudong Lu, Shangyuan Feng.  (2023)  Plasmonic internal standard-decorated nitrocellulose membranes for duplex detection of circulating tumor biomarkers.  SENSORS AND ACTUATORS B-CHEMICAL,  395  (134508).  [PMID:] [10.1016/j.snb.2023.134508]
3. Xin Du, Baohua Kong, Junjie He, Quanyu Zhang, Geer An, Tingting Zhang, Xiufang Xia.  (2023)  Cryoprotective effect of water-tailored trehalose-based natural deep eutectic solvents on frozen-thawed mirror carp (Cyprinus carpio L.) surimi.  FOOD CHEMISTRY,  426  (136633).  [PMID:37329788] [10.1016/j.foodchem.2023.136633]
4. Peng Yan, Xuewei Zheng, Shuang Liu, Yanhua Dong, Tao Fu, Zhongmin Tian, Yayan Wu.  (2023)  Colorimetric Sensor Array for Identification of Proteins and Classification of Metabolic Profiles under Various Osmolyte Conditions.  ACS Sensors,  8  (1): (133–140).  [PMID:36630575] [10.1021/acssensors.2c01847]
5. Liang Huang, Ziyu Shi, Daquan Li, Chenxing Jiang, Xuexue Wang, Mei Huang, Jing Wang, Bin Su.  (2023)  Hue-Recognition Strategy-Based Immunoassay Using Functionalized Dendritic Silica Colloids and Gold Nanoclusters for Point-of-Care Testing of C-Reactive Proteins.  ACS Applied Nano Materials,  6  (1): (86–95).  [PMID:] [10.1021/acsanm.2c03695]
6. Xiang Yu, Lin Zhu, Xiaohui Liang, Bochuan Yuan, Minshu Li, Shen Hu, Pingtian Ding, Lina Du, Junwang Guo, Yiguang Jin.  (2022)  A wearable gamma radiation-responsive granulocyte colony-stimulating factor microneedle system protecting against ionizing radiation-induced injury.  Acta Biomaterialia,  146  (197).  [PMID:35487423] [10.1016/j.actbio.2022.04.040]
7. Tingting Cui, Yaowen Wu, Fanghui Fan.  (2022)  Physicochemical properties and Strength analysis of vitreous encapsulated solids for the safe delivery of β-Carotene.  FOOD RESEARCH INTERNATIONAL,  151  (110877).  [PMID:34980407] [10.1016/j.foodres.2021.110877]
8. Zhang Lu, Li Yingying, Wei Fang, Liu Hang, Wang Yushuai, Zhao Weiman, Dong Zhiyong, Ma Tao, Wang Qingqing.  (2021)  Transdermal Delivery of Salmon Calcitonin Using a Dissolving Microneedle Array: Characterization, Stability, and In vivo Pharmacodynamics.  AAPS PHARMSCITECH,  22  (1): (1-9).  [PMID:33215299] [10.1208/s12249-020-01865-z]
9. Su Zixian, Zhao Guangying, Dou Wenchao.  (2020)  Determination of trace aflatoxin M1 (AFM1) residue in milk by an immunochromatographic assay based on (PEI/PSS)4 red silica nanoparticles.  MICROCHIMICA ACTA,  187  (12): (1-9).  [PMID:33201356] [10.1007/s00604-020-04636-6]
10. Xiang Yu, Minshu Li, Lin Zhu, Jingfei Li, Guoli Zhang, Rongzhen Fang, Zhihong Wu, Yiguang Jin.  (2020)  Amifostine-loaded armored dissolving microneedles for long-term prevention of ionizing radiation-induced injury.  Acta Biomaterialia,  112  (87).  [PMID:32450231] [10.1016/j.actbio.2020.05.025]
11. Shishan Fu, Song Miao, Xiaobin Ma, Tian Ding, Xingqian Ye, Donghong Liu.  (2019)  Inhibition of lactose crystallisation in the presence of galacto-oligosaccharide.  FOOD HYDROCOLLOIDS,  88  (127).  [PMID:] [10.1016/j.foodhyd.2018.09.043]
12. Guiju Xu, Shengju Liu, Jiaxi Peng, Wenping Lv, Ren’an Wu.  (2015)  Facile Synthesis of Gold@Graphitized Mesoporous Silica Nanocomposite and Its Surface-Assisted Laser Desorption/Ionization for Time-of-Flight Mass Spectroscopy.  ACS Applied Materials & Interfaces,  7  (3): (2032–2038).  [PMID:25552293] [10.1021/am507894y]

Solution Calculators

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