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dabuzalgron - 98%, high purity , Alpha-1a adrenergic receptor partial agonist, CAS No.219311-44-1, Alpha-1a adrenergic receptor partial agonist

  • Moligand™
  • ≥98%
Item Number
D609714
Grouped product items
SKUSizeAvailabilityPrice Qty
D609714-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
D609714-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$119.90
D609714-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90
D609714-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$369.90
D609714-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$549.90
D609714-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$789.90
View related series
α1A-adrenoceptor Agonist

Basic Description

Synonyms219311-44-1 (free base) | A911600 | N-(6-Chloro-3-((4,5-dihydro-1H-imidazol-2-yl)methoxy)-2-methylphenyl)methanesulfonamide | Dabuzalgron | HY-117071 | Dabuzalgron [INN] | CHEBI:142452 | GTPL3469 | LGX4GZ74WO | EX-A4502 | METHANESULFONAMIDE, N-(6-CHLORO-3
Specifications & PurityMoligand™, ≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST, PARTIAL AGONIST
Mechanism of actionAlpha-1a adrenergic receptor partial agonist
Product Description

Dabuzalgron (Ro 115-1240) is a selective α-1A adrenergic receptor agonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial function.

Product Properties

ALogP0.9

Associated Targets

ADRA1B Tclin Alpha-1B adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1D Tclin Alpha-1D adrenergic receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADRA1A Tclin Alpha-1A adrenergic receptor 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[6-chloro-3-(4,5-dihydro-1H-imidazol-2-ylmethoxy)-2-methylphenyl]methanesulfonamide
INCHI InChI=1S/C12H16ClN3O3S/c1-8-10(19-7-11-14-5-6-15-11)4-3-9(13)12(8)16-20(2,17)18/h3-4,16H,5-7H2,1-2H3,(H,14,15)
InChi Key FOYWMEJSRSBQGB-UHFFFAOYSA-N
Canonical SMILES Clc1ccc(c(c1NS(=O)(=O)C)C)OCC1=NCCN1
Isomeric SMILES CC1=C(C=CC(=C1NS(=O)(=O)C)Cl)OCC2=NCCN2
PubChem CID 216249
Molecular Weight 317.79

Certificates

Certificate of Analysis(COA)

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Related Documents

Solution Calculators