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Dalpiciclib - 98%, high purity , CAS No.1637781-04-4, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6

  • Moligand™
  • ≥98%
Item Number
D609727
Grouped product items
SKUSizeAvailabilityPrice Qty
D609727-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$143.90
D609727-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,400.90
D609727-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$579.90
D609727-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
D609727-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,849.90

Basic Description

Synonyms6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperidin-4-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one | GTPL11189 | AKOS040759914 | EX-A5817 | Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino)- | DALP
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6

Associated Targets

CDK4 Tclin Cyclin-dependent kinase 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CDK6 Tclin Cyclin-dependent kinase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Molecular Weight 446.54

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2408093Certificate of AnalysisMar 14, 2024 D609727
G2408094Certificate of AnalysisMar 14, 2024 D609727
G2408098Certificate of AnalysisMar 14, 2024 D609727
G2408099Certificate of AnalysisMar 14, 2024 D609727
G2408100Certificate of AnalysisMar 14, 2024 D609727
G2408117Certificate of AnalysisMar 14, 2024 D609727
G2408118Certificate of AnalysisMar 14, 2024 D609727
G2408119Certificate of AnalysisMar 14, 2024 D609727
G2408120Certificate of AnalysisMar 14, 2024 D609727
G2408121Certificate of AnalysisMar 14, 2024 D609727

Related Documents

References

1. Wang J, Li Q, Yuan J, Wang J, Chen Z, Liu Z, Li Z, Lai Y, Gao J, Shen L.  (2017)  CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest..  J Transl Med,  15  (1): (127).  [PMID:28578693]
2. Long F, He Y, Fu H, Li Y, Bao X, Wang Q, Wang Y, Xie C, Lou L.  (2019)  Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, in vitro and in human tumor xenograft models..  Cancer Sci,  110  (4): (1420-1430).  [PMID:30724426]

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