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CAMK:Calcium/calmodulin-dependent protein kinases
DAPK inhibitor 13 , CAS No.D609736, Inhibitor of death associated protein kinase 3

DAPK inhibitor 13 , CAS No.D609736, Inhibitor of death associated protein kinase 3

Item Number

D609736

Grouped product items
SKU	Size	Availability	Price	Qty
D609736-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
D609736-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	compound 13;i-13
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of death associated protein kinase 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	(4E)-2-(4-bromo-3-methylphenyl)-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
INCHI	InChI=1S/C16H11BrN2O2/c1-10-7-12(4-5-13(10)17)15-19-14(16(20)21-15)8-11-3-2-6-18-9-11/h2-9H,1H3/b14-8+
InChi Key	AIDLMCGWDDGYCV-RIYZIHGNSA-N
Canonical SMILES	O=C1OC(=N/C/1=C/c1cccnc1)c1ccc(c(c1)C)Br
Isomeric SMILES	CC1=C(C=CC(=C1)C2=N/C(=C/C3=CN=CC=C3)/C(=O)O2)Br
PubChem CID	56694877

PubChem CID	56694877

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1. Okamoto M, Takayama K, Shimizu T, Muroya A, Furuya T. (2010) Structure-activity relationship of novel DAPK inhibitors identified by structure-based virtual screening.. Bioorg Med Chem, 18 (7): (2728-34). [PMID:20206532]
2. Geering B, Stoeckle C, Rozman S, Oberson K, Benarafa C, Simon HU. (2014) DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants.. J Leukoc Biol, 95 (2): (293-303). [PMID:24163421]

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