Darunavir Ethanolate - 10mM in DMSO, high purity , Human immunodeficiency virus type 1 protease inhibitor, CAS No.635728-49-3(DMSO), Human immunodeficiency virus type 1 protease inhibitor

Item Number

D580365

Grouped product items
SKU	Size	Availability	Price	Qty
D580365-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$184.90

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Basic Description

Synonyms	Darunavir ethanolate\|635728-49-3\|Darunavir (Ethanolate)\|Prezista\|Tmc114 ethanolate\|UNII-33O78XF0BW\|Darunavir monoethanolate\|Rezolsta\|Darunavir (as ethanolate)\|33O78XF0BW\|Darunavir Ethanolate (Prezista)\|SYMTUZA COMPONENT DARUNAVIR\|DARUNAVIR COMPONENT OF SY
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Darunavir ethanolate (TMC114 Ethanolate) is a potent HIV protease inhibitor used to treat and prevent HIV/AIDS. Darunavir has a Ki of 1 nM for wild type HIV-1 protease.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Human immunodeficiency virus type 1 protease inhibitor
Product Description	Darunavir (DRV) is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.

Names and Identifiers

IUPAC Name	[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate;ethanol
INCHI	InChI=1S/C27H37N3O7S.C2H6O/c1-18(2)15-30(38(33,34)21-10-8-20(28)9-11-21)16-24(31)23(14-19-6-4-3-5-7-19)29-27(32)37-25-17-36-26-22(25)12-13-35-26;1-2-3/h3-11,18,22-26,31H,12-17,28H2,1-2H3,(H,29,32);3H,2H2,1H3/t22-,23-,24+,25-,26+;/m0./s1
InChi Key	QWSHKNICRJHQCY-VBTXLZOXSA-N
Canonical SMILES	CCO.CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2COC3C2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
Isomeric SMILES	CCO.CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N
PubChem CID	23725083
Molecular Weight	593.73

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Basic Description