Basic Information
ID: ALA1003027
Type: Binding
Description: Inhibition of GARFTase in human KB cells assessed as inhibition of incorporation of [14C]glycine into [14C]formyl GAR after 30 mins in presence of azaserine
Organism: Homo sapiens
Cell type: KB
Activity Charts
Bioactivity
Activity Types for Assay ALA1003027
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.46 | 0.62 | 0.62 |
| 427.42 | 0.67 | 0.67 |
| 444.47 | 1.40 | 1.40 |
| 458.50 | 1.79 | 1.79 |
| 472.52 | 2.18 | 2.18 |
| 486.55 | 2.57 | 2.57 |
| 500.58 | 2.96 | 2.96 |