Basic Information
ID: ALA1005353
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]alpha-methyl-D-glucopyranoside uptake by fluorescence polarization assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1005353
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.41 | -0.20 | -0.20 |
| 392.88 | 2.01 | 2.01 |
| 380.82 | 1.15 | 1.15 |
| 497.98 | 2.38 | 2.38 |
| 512.00 | 2.72 | 2.72 |
| 752.17 | 4.66 | 4.66 |
| 766.20 | 5.00 | 5.00 |
| 865.33 | 5.33 | 5.33 |
| 879.36 | 5.68 | 5.68 |
| 556.96 | 2.50 | 2.50 |
| 570.99 | 2.53 | 2.53 |
| 795.24 | 6.16 | 6.16 |
| 849.38 | 4.86 | 4.86 |
| 697.97 | ||
| 712.00 | ||
| 712.00 | ||
| 726.03 | ||
| 726.03 | ||
| 740.05 | ||
| 768.11 | ||
| 768.11 | ||
| 782.13 | ||
| 754.08 | ||
| 782.13 | ||
| 994.60 | 5.80 | 5.80 |
| 1008.63 | ||
| 1022.66 | ||
| 1022.66 | ||
| 912.44 | 4.93 | 4.93 |
| 926.46 | 5.28 | 5.28 |
| 774.07 | ||
| 788.10 |