Basic Information
ID: ALA1006150
Type: Binding
Description: Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR in presence of glyburide
Format: BAO_0000219
Organism: Homo sapiens
Cell type: TE-671
Target: Sulfonylurea receptor 2(ALA1971)
Document: ALA1140878
Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR in presence of glyburide: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1006150
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.83 | 3.13 | 3.13 |
| 395.48 | 4.20 | 4.20 |
| 369.42 | 3.94 | 3.94 |
| 396.43 | 3.71 | 3.71 |
| 369.81 | 4.04 | 4.04 |
| 357.79 | 3.64 | 3.64 |
| 356.81 | 3.21 | 3.21 |
| 356.81 | 3.21 | 3.21 |
| 356.81 | 3.21 | 3.21 |
| 356.81 | 3.21 | 3.21 |
| 347.37 | 2.43 | 2.43 |
| 366.37 | 2.29 | 2.29 |
| 391.25 | 3.87 | 3.87 |
| 357.80 | 2.61 | 2.61 |
| 392.86 | 2.76 | 2.76 |
| 356.36 | 2.95 | 2.95 |
| 379.85 | 4.20 | 4.20 |
| 379.85 | 4.20 | 4.20 |
| 379.85 | 4.20 | 4.20 |
| 359.43 | 3.85 | 3.85 |
| 345.40 | 3.54 | 3.54 |
| 354.84 | 4.32 | 4.32 |
| 321.38 | 3.07 | 3.07 |
| 355.83 | 3.72 | 3.72 |
| 355.83 | 3.72 | 3.72 |
| 355.83 | 3.72 | 3.72 |
| 362.39 | 2.48 | 2.48 |
| 385.88 | 4.45 | 4.45 |
| 370.79 | 4.00 | 4.00 |
| 352.42 | 3.82 | 3.82 |
| 369.81 | 4.04 | 4.04 |
| 368.82 | 3.77 | 3.77 |
| 484.96 | 5.00 | 5.00 |
| 502.95 | 5.14 | 5.14 |
| 479.99 | 4.20 | 4.20 |
| 413.69 | 5.47 | 5.47 |
| 448.91 | 5.40 | 5.40 |
| 336.35 | 2.59 | 2.59 |
| 370.79 | 3.24 | 3.24 |
| 370.79 | 3.24 | 3.24 |
| 352.42 | 3.06 | 3.06 |
| 397.41 | 2.96 | 2.96 |
| 485.95 | 4.20 | 4.20 |
| 485.95 | 4.20 | 4.20 |
| 492.98 | 3.54 | 3.54 |
| 480.97 | 3.40 | 3.40 |
| 414.67 | 4.68 | 4.68 |
| 449.89 | 4.60 | 4.60 |
| 515.97 | 4.21 | 4.21 |
| 520.39 | 4.86 | 4.86 |
| 503.94 | 4.34 | 4.34 |
| 382.80 | 3.08 | 3.08 |
| 349.35 | 1.82 | 1.82 |