Basic Information
ID: ALA1006172
Type: Functional
Description: Inhibition of human OX1 receptor expressed in CHO cells assessed as intercellular calcium mobilization by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Orexin receptor 1(ALA5113)
Document: ALA1143438
Inhibition of human OX1 receptor expressed in CHO cells assessed as intercellular calcium mobilization by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1006172
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.59 | 4.36 | 4.36 |
| 420.53 | 3.08 | 3.08 |
| 484.02 | 3.49 | 3.49 |
| 394.92 | 3.71 | 3.71 |
| 378.47 | 3.20 | 3.20 |
| 474.58 | 2.71 | 2.71 |
| 465.96 | 3.29 | 3.29 |
| 508.95 | 4.44 | 4.44 |
| 479.60 | 2.84 | 2.84 |
| 474.58 | 2.71 | 2.71 |
| 484.02 | 3.49 | 3.49 |
| 445.54 | 2.95 | 2.95 |
| 484.02 | 3.49 | 3.49 |
| 454.98 | 3.73 | 3.73 |
| 483.03 | 4.54 | 4.54 |
| 512.07 | 4.27 | 4.27 |
| 498.05 | 3.88 | 3.88 |
| 510.06 | 4.02 | 4.02 |
| 506.02 | 4.21 | 4.21 |
| 512.05 | 4.34 | 4.34 |
| 547.08 | 4.38 | 4.38 |
| 548.07 | 3.77 | 3.77 |
| 536.05 | 3.41 | 3.41 |
| 550.08 | 3.71 | 3.71 |
| 561.09 | 4.92 | 4.92 |
| 575.11 | 5.23 | 5.23 |
| 388.53 | 3.62 | 3.62 |
| 374.51 | 3.37 | 3.37 |
| 390.51 | 3.07 | 3.07 |
| 439.38 | 3.82 | 3.82 |
| 378.47 | 3.20 | 3.20 |
| 385.49 | 2.93 | 2.93 |
| 444.48 | 3.96 | 3.96 |
| 374.51 | 3.37 | 3.37 |
| 394.92 | 3.71 | 3.71 |
| 378.47 | 3.20 | 3.20 |
| 374.51 | 3.37 | 3.37 |