Basic Information
ID: ALA1011147
Type: Binding
Description: Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as reduction in doxorubicin IC50 at IC5 pretreated for 6 hrs before doxorubicin administration measured after 3 days by MTT assay
Organism: Homo sapiens
Cell type: A2780 ADR
Activity Charts
Bioactivity
Activity Types for Assay ALA1011147
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.53 | 3.37 | 3.37 |
| 276.32 | 1.90 | 1.90 |
| 282.71 | 1.86 | 1.86 |
| 307.29 | 1.50 | 1.50 |
| 330.29 | 2.61 | 2.61 |
| 262.29 | 1.59 | 1.59 |
| 248.26 | 1.20 | 1.20 |
| 296.74 | 2.25 | 2.25 |
| 307.29 | 1.50 | 1.50 |
| 292.32 | 1.60 | 1.60 |
| 352.84 | 4.07 | 4.07 |
| 397.29 | 4.18 | 4.18 |
| 364.85 | 4.24 | 4.24 |
| 549.22 | 9.53 | 9.53 |
| 355.21 | 3.01 | 3.01 |
| 366.87 | 4.46 | 4.46 |
| 507.14 | 8.36 | 8.36 |
| 411.32 | 4.57 | 4.57 |
| 409.31 | 4.35 | 4.35 |
| 364.85 | 4.24 | 4.24 |
| 369.24 | 3.40 | 3.40 |
| 593.67 | 9.64 | 9.64 |