Basic Information
ID: ALA1011151
Type: Binding
Description: Reversal of P-gp 170-mediated multidrug resistance in human A2780/DX3 cells assessed as increase in intracellular doxorubicin accumulation at 5 times IC5 pretreated for 2 hrs before doxorubicin administration measured after 2 hrs by epifluorescent microscopic analysis
Organism: Homo sapiens
Cell type: A2780 ADR
Activity Charts
Bioactivity
Activity Types for Assay ALA1011151
Activity_index
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.53 | 0.00 | 0.00 |
| 248.26 | 1.20 | 1.20 |
| 366.87 | 4.46 | 4.46 |
| 411.32 | 4.57 | 4.57 |
| 364.85 | 4.24 | 4.24 |