Basic Information
ID: ALA1014417
Type: Binding
Description: Inhibition of PGES1 in human A549 cell microsome assessed as PGE2 formation at 10 uM by cell-free assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Prostaglandin E synthase(ALA5658)
Document: ALA1151733
Inhibition of PGES1 in human A549 cell microsome assessed as PGE2 formation at 10 uM by cell-free assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1014417
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 323.81 | 3.67 | 3.67 |
| 283.33 | 3.73 | 3.73 |
| 337.83 | 4.06 | 4.06 |
| 399.90 | 5.41 | 5.41 |
| 407.97 | 6.01 | 6.01 |
| 436.02 | 6.48 | 6.48 |
| 430.96 | 5.94 | 5.94 |
| 459.02 | 6.42 | 6.42 |
| 431.95 | 5.99 | 5.99 |
| 444.99 | 5.81 | 5.81 |
| 436.02 | 6.79 | 6.79 |
| 449.96 | 6.56 | 6.56 |
| 498.09 | 7.40 | 7.40 |
| 481.02 | 6.93 | 6.93 |
| 481.02 | 6.93 | 6.93 |
| 575.96 | 7.27 | 7.27 |
| 481.02 | 6.93 | 6.93 |
| 500.06 | 7.37 | 7.37 |
| 351.86 | 4.45 | 4.45 |
| 379.91 | 5.23 | 5.23 |
| 410.50 | 3.90 | 3.90 |
| 466.60 | 5.46 | 5.46 |
| 494.66 | 5.93 | 5.93 |
| 407.97 | 5.30 | 5.30 |
| 423.97 | 5.14 | 5.14 |
| 452.02 | 5.62 | 5.62 |
| 456.01 | 7.06 | 7.06 |
| 470.04 | 6.92 | 6.92 |