Basic Information
ID: ALA1015213
Type: ADME
Description: Inhibition of CYP3A1/CYP3A2-catalyzed erythromycin N-demethylase activity in dexamethasone-treated Sprague-Dawley rat liver microsomes by spectrophotometry
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA1015213
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.96 | 4.78 | 4.78 |
| 361.24 | 3.25 | 3.25 |
| 451.42 | 5.07 | 5.07 |
| 530.32 | 5.84 | 5.84 |
| 457.47 | 5.35 | 5.35 |
| 501.48 | 6.23 | 6.23 |
| 451.35 | 4.07 | 4.07 |
| 514.25 | 5.12 | 5.12 |
| 460.36 | 4.23 | 4.23 |
| 389.35 | 3.64 | 3.64 |
| 525.33 | 4.47 | 4.47 |