Basic Information
ID: ALA1017607
Type: Binding
Description: Inhibition of voltage-gated sodium channel in Wistar rat forebrain synaptosomes assessed as inhibition of [14C]guanidium ion flux
Organism: Rattus norvegicus
Strain: Wistar
Tissue: Brain
Subcellular Fraction: Synaptosomes
Activity Charts
Bioactivity
Activity Types for Assay ALA1017607
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.10 | 2.01 | 2.01 |
| 372.69 | 3.44 | 3.44 |
| 515.55 | 3.37 | 3.37 |
| 321.57 | 3.74 | 3.74 |
| 405.46 | 4.16 | 4.16 |
| 419.49 | 4.47 | 4.47 |
| 419.49 | 4.47 | 4.47 |
| 419.49 | 4.47 | 4.47 |
| 419.49 | 4.47 | 4.47 |
| 433.51 | 4.78 | 4.78 |
| 433.51 | 4.78 | 4.78 |
| 455.52 | 5.31 | 5.31 |
| 449.47 | 3.89 | 3.89 |
| 449.47 | 3.89 | 3.89 |
| 435.48 | 4.17 | 4.17 |
| 495.54 | 4.19 | 4.19 |
| 448.48 | 3.26 | 3.26 |
| 462.51 | 4.12 | 4.12 |
| 439.90 | 4.81 | 4.81 |
| 439.90 | 4.81 | 4.81 |
| 439.90 | 4.81 | 4.81 |
| 459.43 | 4.58 | 4.58 |
| 489.45 | 5.06 | 5.06 |
| 473.46 | 5.18 | 5.18 |
| 471.52 | 4.55 | 4.55 |
| 473.49 | 4.21 | 4.21 |
| 305.34 | 2.59 | 2.59 |
| 305.34 | 2.59 | 2.59 |
| 319.37 | 2.90 | 2.90 |
| 319.37 | 2.90 | 2.90 |
| 319.37 | 2.90 | 2.90 |
| 319.37 | 2.90 | 2.90 |
| 333.40 | 3.21 | 3.21 |
| 333.40 | 3.21 | 3.21 |
| 355.40 | 3.75 | 3.75 |
| 349.35 | 2.32 | 2.32 |
| 349.35 | 2.32 | 2.32 |
| 335.37 | 2.60 | 2.60 |
| 395.42 | 2.62 | 2.62 |
| 348.37 | 1.69 | 1.69 |
| 362.39 | 2.55 | 2.55 |
| 339.79 | 3.25 | 3.25 |
| 339.79 | 3.25 | 3.25 |
| 339.79 | 3.25 | 3.25 |
| 359.31 | 3.01 | 3.01 |
| 389.34 | 3.49 | 3.49 |
| 373.34 | 3.61 | 3.61 |
| 371.40 | 2.98 | 2.98 |
| 373.38 | 2.64 | 2.64 |
| 419.49 | 4.35 | 4.35 |
| 419.49 | 4.35 | 4.35 |
| 435.48 | 4.19 | 4.19 |
| 319.37 | 2.79 | 2.79 |
| 319.37 | 2.79 | 2.79 |
| 335.37 | 2.62 | 2.62 |
| 215.22 | 1.07 | 1.07 |
| 415.43 | 1.80 | 1.80 |
| 257.25 | 1.21 | 1.21 |
| 405.46 | 4.16 | 4.16 |
| 439.48 | 4.56 | 4.56 |
| 409.45 | 4.06 | 4.06 |
| 357.37 | 2.77 | 2.77 |
| 445.50 | 3.61 | 3.61 |
| 315.33 | 2.64 | 2.64 |