Basic Information
ID: ALA1019822
Type: Binding
Description: Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of TNF-alpha-induced transcriptional activation at 10 uM treated 24 hrs before TNFalpha challenge measured after 20 to 24 hrs by luciferase assay relative to control
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1019822
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.88 | 4.51 | 4.51 |
| 444.95 | 6.21 | 6.21 |
| 479.39 | 6.87 | 6.87 |
| 390.47 | 4.06 | 4.06 |
| 452.54 | 5.76 | 5.76 |
| 486.98 | 6.42 | 6.42 |
| 480.38 | 6.14 | 6.14 |
| 487.97 | 5.69 | 5.69 |
| 507.02 | 7.57 | 7.57 |
| 521.05 | 7.88 | 7.88 |
| 541.46 | 8.23 | 8.23 |
| 521.05 | 7.88 | 7.88 |
| 452.54 | 5.42 | 5.42 |
| 549.06 | 7.78 | 7.78 |
| 410.50 | 5.56 | 5.56 |
| 444.95 | 6.21 | 6.21 |
| 362.46 | 4.17 | 4.17 |
| 424.53 | 5.87 | 5.87 |
| 458.97 | 6.52 | 6.52 |
| 362.46 | 4.17 | 4.17 |
| 458.97 | 6.52 | 6.52 |
| 458.97 | 6.52 | 6.52 |
| 474.97 | 6.22 | 6.22 |
| 474.97 | 6.22 | 6.22 |
| 444.95 | 6.21 | 6.21 |
| 479.39 | 6.87 | 6.87 |