Basic Information
ID: ALA1019824
Type: Binding
Description: Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of TNF-alpha-induced transcriptional activation treated 24 hrs before TNFalpha challenge measured after 20 to 24 hrs by luciferase assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1019824
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.88 | 4.51 | 4.51 |
| 444.95 | 6.21 | 6.21 |
| 479.39 | 6.87 | 6.87 |
| 390.47 | 4.06 | 4.06 |
| 362.46 | 4.17 | 4.17 |
| 424.53 | 5.87 | 5.87 |
| 474.97 | 6.22 | 6.22 |