Basic Information
ID: ALA1020203
Type: Binding
Description: Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS method
Organism: Mus musculus
Cell type: P388/S
Activity Charts
Bioactivity
Activity Types for Assay ALA1020203
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 608.56 | -0.73 | -0.73 |
| 640.61 | 1.37 | 1.37 |
| 630.57 | 0.96 | 0.96 |
| 630.57 | 0.96 | 0.96 |
| 629.58 | 0.70 | 0.70 |
| 641.59 | 0.76 | 0.76 |
| 641.59 | 0.76 | 0.76 |
| 641.59 | 0.76 | 0.76 |
| 642.58 | 0.16 | 0.16 |
| 691.65 | 1.92 | 1.92 |
| 691.65 | 1.92 | 1.92 |
| 691.65 | 1.92 | 1.92 |
| 654.63 | 1.68 | 1.68 |
| 685.60 | 1.28 | 1.28 |
| 719.50 | 2.13 | 2.13 |
| 665.62 | 1.24 | 1.24 |
| 656.60 | 1.08 | 1.08 |
| 670.63 | 0.86 | 0.86 |
| 656.60 | 1.08 | 1.08 |
| 670.63 | 0.86 | 0.86 |
| 670.63 | 0.86 | 0.86 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |
| 671.62 | 0.26 | 0.26 |