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Assay Report Card

Basic Information

ID: ALA1020204

Type: Binding

Description: Inhibition of human DNA topoisomerase 1-mediated DNA cleavage assessed as relaxation of supercoiled pBR322 plasmid DNA after 15 mins by densitometer

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA1020204

EC50

Total(30)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
608.56-0.73-0.73
640.611.371.37
630.570.960.96
630.570.960.96
629.580.700.70
641.590.760.76
641.590.760.76
641.590.760.76
642.580.160.16
691.651.921.92
691.651.921.92
691.651.921.92
654.631.681.68
685.601.281.28
719.502.132.13
665.621.241.24
656.601.081.08
670.630.860.86
656.601.081.08
670.630.860.86
670.630.860.86
671.620.260.26
671.620.260.26
671.620.260.26
671.620.260.26
671.620.260.26
671.620.260.26
671.620.260.26
671.620.260.26
671.620.260.26
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