Basic Information
ID: ALA1021066
Type: ADME
Description: Ratio of permeability from apical to basolateral side after 1 hr of drug washout by methanol to apical to basolateral side in MDCK2 cell monolayer over expressing MDR1 at 5 uM after 1 hr of drug washout by methanol in presence LSN335984
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK-II
Target: ADMET(ALA612558)
Document: ALA1138514
Ratio of permeability from apical to basolateral side after 1 hr of drug washout by methanol to apical to basolateral side in MDCK2 cell monolayer over expressing MDR1 at 5 uM after 1 hr of drug washout by methanol in presence LSN335984: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1021066
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 656.53 | ||
| 439.42 | 4.77 | 4.77 |
| 556.56 | 5.40 | 5.40 |
| 603.45 | ||
| 469.45 | 4.78 | 4.78 |
| 564.53 | 4.79 | 4.79 |
| 611.43 | ||
| 601.41 | ||
| 637.72 | 5.99 | 5.99 |
| 684.61 | ||
| 689.80 | 6.63 | 6.63 |
| 534.51 | 4.78 | 4.78 |
| 553.53 | 3.93 | 3.93 |
| 471.83 | 5.04 | 5.04 |