Assay Report Card

Basic Information

ID: ALA1021377

Type: Binding

Description: Inhibition of purified human recombinant APE1 expressed in Escherichia coli M15 cells

Organism: Homo sapiens

Cell type: M15

Activity Charts

Bioactivity

Activity Types for Assay ALA1021377

IC50

Total(171)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
423.42	2.29	2.29
468.51	2.39	2.39
307.73	2.91	2.91
279.32	2.32	2.32
294.38	1.67	1.67
408.44	3.73	3.73
458.47	3.77	3.77
442.40	3.41	3.41
378.39	0.77	0.77
310.33	3.32	3.32
265.26	0.66	0.66
343.36	0.88	0.88
287.25	0.32	0.32
275.27	0.79	0.79
250.21	0.34	0.34
804.91	-2.73	-2.73
271.30	0.80	0.80
362.43	0.04	0.04
252.25	2.00	2.00
297.36	2.27	2.27
326.35	3.05	3.05
397.37	3.69	3.69
396.39	3.43	3.43
380.38	4.19	4.19
368.46	1.02	1.02
386.51	2.95	2.95
376.43	2.67	2.67
404.47	3.53	3.53
421.95	3.87	3.87
454.63	4.07	4.07
363.44	2.38	2.38
324.43	2.13	2.13
456.62	4.53	4.53
415.54	3.43	3.43
441.55	1.95	1.95
398.49	2.59	2.59
405.48	1.11	1.11
386.50	2.42	2.42
369.51	3.18	3.18
472.50	3.69	3.69
294.33	2.12	2.12
250.21	-0.03	-0.03
258.30	2.24	2.24
310.33	3.32	3.32
392.41	1.16	1.16
455.47	1.74	1.74
475.35	3.66	3.66
370.45	4.05	4.05
310.33	3.32	3.32
363.40	1.79	1.79
234.21	1.28	1.28
512.52	2.38	2.38
528.98	2.90	2.90
456.52	3.07	3.07
384.44	1.70	1.70
319.71	1.47	1.47
394.79	1.82	1.82
382.46	1.98	1.98
320.39	0.56	0.56
236.27	0.14	0.14
335.37	2.19	2.19
415.49	4.28	4.28
408.91	3.86	3.86
346.41	2.43	2.43
531.06	4.80	4.80
401.49	2.19	2.19
366.44	3.75	3.75
423.52	3.96	3.96
457.96	4.61	4.61
394.88	3.47	3.47
431.43	3.13	3.13
341.42	0.43	0.43
356.43	1.12	1.12
471.61	2.75	2.75
464.53	1.78	1.78
422.56	3.37	3.37
464.55	2.85	2.85
486.50	2.82	2.82
402.48	1.50	1.50
387.44	3.44	3.44
428.43	2.24	2.24
320.35	0.98	0.98
406.44	1.55	1.55
372.33	2.65	2.65
306.23	1.06	1.06
275.26	1.96	1.96
336.39	2.50	2.50
298.25	-0.47	-0.47
290.27	2.87	2.87
389.41	2.93	2.93
560.47	3.92	3.92
406.44	3.12	3.12
239.26	0.50	0.50
287.31	2.57	2.57
291.28	2.40	2.40
246.26	3.17	3.17
285.32	3.82	3.82
256.32	2.70	2.70
288.10	2.03	2.03
310.35	3.68	3.68
289.29	-0.45	-0.45
273.20	-2.35	-2.35
210.21	-0.65	-0.65
194.21	-0.32	-0.32
212.23	1.56	1.56
291.30	2.21	2.21
314.41	2.50	2.50
454.44	-0.38	-0.38
319.36	-0.20	-0.20
400.43	1.34	1.34
432.43	2.94	2.94
344.37	1.01	1.01
366.49	0.50	0.50
384.37	0.29	0.29
352.36	-0.61	-0.61
374.22	0.75	0.75
422.44	2.46	2.46
310.33	3.32	3.32
242.27	1.85	1.85
348.38	1.67	1.67
214.18	-1.27	-1.27
213.15	-2.12	-2.12
283.33	2.25	2.25
465.45	3.78	3.78
305.40	1.64	1.64
210.28	-0.01	-0.01
257.22	1.47	1.47
209.22	-2.18	-2.18
470.69	4.45	4.45
267.27	0.68	0.68
394.41	-0.50	-0.50
387.44	2.82	2.82
400.53	3.41	3.41
419.57	3.63	3.63
356.44	1.84	1.84
438.57	3.74	3.74
423.50	2.58	2.58
327.40	1.72	1.72
437.54	4.09	4.09
359.39	3.18	3.18
347.41	2.98	2.98
349.38	1.82	1.82
375.42	0.26	0.26
415.47	1.40	1.40
394.45	1.93	1.93
408.52	3.08	3.08
402.93	3.04	3.04
545.33	4.50	4.50
345.38	1.18	1.18
483.54	2.99	2.99
332.38	3.11	3.11
384.43	3.90	3.90
468.62	3.85	3.85
470.94	3.11	3.11
504.37	3.42	3.42
307.38	1.19	1.19
451.44	2.83	2.83
447.47	1.67	1.67
351.43	1.53	1.53
505.64	3.02	3.02
377.51	3.78	3.78
450.63	3.75	3.75
376.48	2.37	2.37
568.97	4.10	4.10
387.58	1.62	1.62
389.51	2.02	2.02
437.52	2.84	2.84
315.35	0.48	0.48
450.52	3.14	3.14
370.47	1.36	1.36
448.01	1.84	1.84