Basic Information
ID: ALA1023606
Type: Binding
Description: Inhibition of eukaryotic initiation factor 4E in micrococcal nuclease-pretreated rabbit reticulocyte lysate assessed as inhibition of m7,3'-O-GpppG-capped 5'UTRbetaglob-LUC mRNA translation treated 60 mins before mRNA addition by luciferase-based luminometry
Organism: Oryctolagus cuniculus
Activity Charts
Bioactivity
Activity Types for Assay ALA1023606
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 537.21 | -3.54 | -3.54 |
| 802.44 | -4.77 | -4.77 |
| 818.51 | -3.83 | -3.83 |
| 818.51 | -3.83 | -3.83 |
| 553.28 | -2.19 | -2.19 |
| 555.29 | -2.88 | -2.88 |