Basic Information
ID: ALA1024607
Type: Binding
Description: Inhibition of human Nav1.5 channel expressed in HEK293 cells assessed as blockade of veratridine-induced late inward sodium current elicited at -30 mV from holding potential -90 mV at 10 uM by patch clamp method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1024607
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 375.56 | 4.57 | 4.57 |
| 319.27 | -5.52 | -5.52 |
| 359.56 | 4.87 | 4.87 |
| 389.59 | 4.87 | 4.87 |
| 403.61 | 5.39 | 5.39 |
| 379.52 | 4.40 | 4.40 |
| 404.56 | 3.36 | 3.36 |
| 389.59 | 4.83 | 4.83 |
| 385.55 | 5.30 | 5.30 |
| 386.54 | 4.70 | 4.70 |
| 378.54 | 4.28 | 4.28 |
| 374.58 | 4.45 | 4.45 |
| 387.57 | 4.49 | 4.49 |
| 385.56 | 4.43 | 4.43 |
| 389.59 | 4.96 | 4.96 |
| 375.56 | 4.57 | 4.57 |
| 389.59 | 4.36 | 4.36 |
| 390.57 | 4.15 | 4.15 |
| 391.56 | 4.27 | 4.27 |
| 389.54 | 4.29 | 4.29 |
| 384.57 | 5.04 | 5.04 |
| 376.55 | 3.85 | 3.85 |