Basic Information
ID: ALA1026068
Type: Binding
Description: Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screening
Format: BAO_0000219
Organism: Homo sapiens
Cell type: AU565
Target: Heat shock protein HSP90(ALA2095165)
Document: ALA1158466
Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screening: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1026068
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 585.70 | 2.54 | 2.54 |
| 368.48 | 4.22 | 4.22 |
| 369.47 | 3.10 | 3.10 |
| 417.51 | 4.79 | 4.79 |
| 366.47 | 3.26 | 3.26 |
| 418.52 | 2.24 | 2.24 |
| 384.48 | 2.88 | 2.88 |
| 463.53 | 4.50 | 4.50 |
| 464.49 | 3.86 | 3.86 |
| 448.54 | 4.37 | 4.37 |
| 392.46 | 3.64 | 3.64 |
| 617.65 | 3.37 | 3.37 |
| 404.54 | 5.19 | 5.19 |
| 477.56 | 4.81 | 4.81 |
| 378.48 | 3.57 | 3.57 |
| 477.56 | 4.81 | 4.81 |
| 424.55 | 3.40 | 3.40 |
| 446.50 | 3.78 | 3.78 |
| 468.48 | 3.22 | 3.22 |
| 464.49 | 3.86 | 3.86 |
| 410.52 | 3.15 | 3.15 |
| 438.57 | 3.97 | 3.97 |
| 396.49 | 3.03 | 3.03 |
| 366.47 | 3.40 | 3.40 |
| 386.52 | 3.21 | 3.21 |
| 380.49 | 2.45 | 2.45 |
| 449.51 | 4.17 | 4.17 |
| 387.48 | 4.78 | 4.78 |
| 423.56 | 4.06 | 4.06 |
| 415.54 | 5.21 | 5.21 |
| 491.51 | 3.57 | 3.57 |
| 296.37 | 3.04 | 3.04 |
| 366.51 | 4.77 | 4.77 |
| 367.49 | 4.25 | 4.25 |
| 409.53 | 3.76 | 3.76 |
| 450.58 | 3.79 | 3.79 |
| 424.55 | 2.78 | 2.78 |