Basic Information
ID: ALA1027431
Type: Binding
Description: Inhibition of wild type-TTR expressed in Escherichia coli assessed as amyloid fibril formation at pH 4.4 at 7. 2 uM after 72 hrs by acid-mediated aggregation assay relative to control
Activity Charts
Bioactivity
Activity Types for Assay ALA1027431
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.30 | 4.18 | 4.18 |
| 353.01 | 5.02 | 5.02 |
| 223.28 | 4.11 | 4.11 |
| 369.01 | 4.73 | 4.73 |
| 239.27 | 3.82 | 3.82 |
| 371.03 | 4.17 | 4.17 |
| 240.31 | 3.95 | 3.95 |
| 208.30 | 4.47 | 4.47 |
| 338.04 | 5.38 | 5.38 |
| 354.04 | 5.09 | 5.09 |
| 182.27 | 3.97 | 3.97 |
| 312.00 | 4.88 | 4.88 |
| 198.26 | 3.68 | 3.68 |
| 328.00 | 4.58 | 4.58 |
| 210.32 | 4.09 | 4.09 |
| 226.32 | 3.79 | 3.79 |
| 327.02 | 4.96 | 4.96 |
| 213.28 | 3.75 | 3.75 |
| 343.02 | 4.66 | 4.66 |
| 198.26 | 4.10 | 4.10 |
| 328.00 | 5.00 | 5.00 |
| 214.26 | 3.80 | 3.80 |
| 344.00 | 4.71 | 4.71 |
| 370.04 | 4.86 | 4.86 |
| 256.30 | 3.65 | 3.65 |
| 386.04 | 4.56 | 4.56 |
| 261.35 | 3.10 | 3.10 |
| 391.08 | 4.01 | 4.01 |
| 277.35 | 2.81 | 2.81 |
| 407.08 | 3.72 | 3.72 |
| 225.29 | 3.56 | 3.56 |
| 355.03 | 4.46 | 4.46 |
| 241.29 | 3.26 | 3.26 |
| 371.03 | 4.17 | 4.17 |
| 225.29 | 3.56 | 3.56 |
| 355.03 | 4.46 | 4.46 |
| 241.29 | 3.26 | 3.26 |
| 356.06 | 4.70 | 4.70 |
| 197.28 | 4.05 | 4.05 |
| 340.06 | 5.00 | 5.00 |