Assay Report Card

Basic Information

ID: ALA1027436

Type: Functional

Description: Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
294.361.351.35
294.361.351.35
319.412.632.63
270.340.870.87
270.340.870.87
306.321.151.15
300.370.880.88
300.370.880.88
271.330.270.27
301.350.280.28
301.421.961.96
259.320.000.00
259.320.200.20
273.340.210.21
259.320.200.20
273.340.210.21
277.33-0.66-0.66
286.34-0.04-0.04
285.391.971.97
249.361.111.11
294.361.351.35
250.350.500.50
249.361.111.11
249.361.111.11
293.371.951.95
293.371.951.95
248.372.592.59
248.372.172.17
280.341.011.01
263.391.501.50
306.461.041.04
237.351.331.33
251.381.351.35
265.401.741.74
238.341.301.30
234.351.531.53
263.391.571.57
277.421.591.59
268.792.182.18
250.351.231.23
264.371.531.53
193.25-0.19-0.19
207.280.120.12
223.28-0.18-0.18
208.27-0.61-0.61
269.351.481.48
207.280.120.12
327.482.282.28
227.700.460.46
319.150.420.42
209.25-0.48-0.48
223.28-0.18-0.18
208.27-0.61-0.61
222.30-0.15-0.15
236.32-0.12-0.12
264.380.660.66
262.360.410.41
305.43-0.05-0.05
276.390.800.80
278.36-0.35-0.35
291.40-0.44-0.44
284.371.551.55
298.391.421.42
269.351.481.48
283.381.791.79
283.381.791.79
283.381.791.79
299.381.491.49
299.381.491.49
299.381.491.49
329.401.491.49
303.802.132.13
303.802.132.13
395.252.082.08
395.252.082.08
308.391.661.66
324.391.361.36