ID: ALA1027436
Type: Functional
Description: Agonist activity at rat histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay
Organism: Rattus norvegicus
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA1027436
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
294.36 | 1.35 | 1.35 |
294.36 | 1.35 | 1.35 |
319.41 | 2.63 | 2.63 |
270.34 | 0.87 | 0.87 |
270.34 | 0.87 | 0.87 |
306.32 | 1.15 | 1.15 |
300.37 | 0.88 | 0.88 |
300.37 | 0.88 | 0.88 |
271.33 | 0.27 | 0.27 |
301.35 | 0.28 | 0.28 |
301.42 | 1.96 | 1.96 |
259.32 | 0.00 | 0.00 |
259.32 | 0.20 | 0.20 |
273.34 | 0.21 | 0.21 |
259.32 | 0.20 | 0.20 |
273.34 | 0.21 | 0.21 |
277.33 | -0.66 | -0.66 |
286.34 | -0.04 | -0.04 |
285.39 | 1.97 | 1.97 |
249.36 | 1.11 | 1.11 |
294.36 | 1.35 | 1.35 |
250.35 | 0.50 | 0.50 |
249.36 | 1.11 | 1.11 |
249.36 | 1.11 | 1.11 |
293.37 | 1.95 | 1.95 |
293.37 | 1.95 | 1.95 |
248.37 | 2.59 | 2.59 |
248.37 | 2.17 | 2.17 |
280.34 | 1.01 | 1.01 |
263.39 | 1.50 | 1.50 |
306.46 | 1.04 | 1.04 |
237.35 | 1.33 | 1.33 |
251.38 | 1.35 | 1.35 |
265.40 | 1.74 | 1.74 |
238.34 | 1.30 | 1.30 |
234.35 | 1.53 | 1.53 |
263.39 | 1.57 | 1.57 |
277.42 | 1.59 | 1.59 |
268.79 | 2.18 | 2.18 |
250.35 | 1.23 | 1.23 |
264.37 | 1.53 | 1.53 |
193.25 | -0.19 | -0.19 |
207.28 | 0.12 | 0.12 |
223.28 | -0.18 | -0.18 |
208.27 | -0.61 | -0.61 |
269.35 | 1.48 | 1.48 |
207.28 | 0.12 | 0.12 |
327.48 | 2.28 | 2.28 |
227.70 | 0.46 | 0.46 |
319.15 | 0.42 | 0.42 |
209.25 | -0.48 | -0.48 |
223.28 | -0.18 | -0.18 |
208.27 | -0.61 | -0.61 |
222.30 | -0.15 | -0.15 |
236.32 | -0.12 | -0.12 |
264.38 | 0.66 | 0.66 |
262.36 | 0.41 | 0.41 |
305.43 | -0.05 | -0.05 |
276.39 | 0.80 | 0.80 |
278.36 | -0.35 | -0.35 |
291.40 | -0.44 | -0.44 |
284.37 | 1.55 | 1.55 |
298.39 | 1.42 | 1.42 |
269.35 | 1.48 | 1.48 |
283.38 | 1.79 | 1.79 |
283.38 | 1.79 | 1.79 |
283.38 | 1.79 | 1.79 |
299.38 | 1.49 | 1.49 |
299.38 | 1.49 | 1.49 |
299.38 | 1.49 | 1.49 |
329.40 | 1.49 | 1.49 |
303.80 | 2.13 | 2.13 |
303.80 | 2.13 | 2.13 |
395.25 | 2.08 | 2.08 |
395.25 | 2.08 | 2.08 |
308.39 | 1.66 | 1.66 |
324.39 | 1.36 | 1.36 |