Basic Information
ID: ALA1027438
Type: Functional
Description: Antagonist activity at human histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1027438
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 277.76 | 2.21 | 2.21 |
| 294.36 | 1.35 | 1.35 |
| 294.36 | 1.35 | 1.35 |
| 345.45 | 3.14 | 3.14 |
| 345.45 | 3.14 | 3.14 |
| 345.45 | 3.14 | 3.14 |
| 319.41 | 2.63 | 2.63 |
| 319.41 | 2.63 | 2.63 |
| 270.34 | 0.87 | 0.87 |
| 270.34 | 0.87 | 0.87 |
| 306.32 | 1.15 | 1.15 |
| 300.37 | 0.88 | 0.88 |
| 271.33 | 0.27 | 0.27 |
| 301.35 | 0.28 | 0.28 |
| 301.42 | 1.96 | 1.96 |
| 335.42 | 1.66 | 1.66 |
| 273.34 | 0.21 | 0.21 |
| 259.32 | 0.20 | 0.20 |
| 273.34 | 0.21 | 0.21 |
| 277.33 | -0.66 | -0.66 |
| 285.39 | 1.97 | 1.97 |
| 249.36 | 1.11 | 1.11 |
| 294.36 | 1.35 | 1.35 |
| 250.35 | 0.50 | 0.50 |
| 249.36 | 1.11 | 1.11 |
| 249.36 | 1.11 | 1.11 |
| 293.37 | 1.95 | 1.95 |
| 293.37 | 1.95 | 1.95 |
| 248.37 | 2.59 | 2.59 |
| 248.37 | 2.17 | 2.17 |
| 280.34 | 1.01 | 1.01 |
| 263.39 | 1.50 | 1.50 |
| 334.43 | 2.13 | 2.13 |
| 306.46 | 1.04 | 1.04 |
| 237.35 | 1.33 | 1.33 |
| 251.38 | 1.35 | 1.35 |
| 265.40 | 1.74 | 1.74 |
| 238.34 | 1.30 | 1.30 |
| 234.35 | 1.53 | 1.53 |
| 263.39 | 1.57 | 1.57 |
| 250.35 | 1.23 | 1.23 |
| 207.28 | 0.12 | 0.12 |
| 223.28 | -0.18 | -0.18 |
| 269.35 | 1.48 | 1.48 |
| 207.28 | 0.12 | 0.12 |
| 327.48 | 2.28 | 2.28 |
| 227.70 | 0.46 | 0.46 |
| 319.15 | 0.42 | 0.42 |
| 209.25 | -0.48 | -0.48 |
| 223.28 | -0.18 | -0.18 |
| 208.27 | -0.61 | -0.61 |
| 222.30 | -0.15 | -0.15 |
| 236.32 | -0.12 | -0.12 |
| 264.38 | 0.66 | 0.66 |
| 262.36 | 0.41 | 0.41 |
| 305.43 | -0.05 | -0.05 |
| 276.39 | 0.80 | 0.80 |
| 278.36 | -0.35 | -0.35 |
| 291.40 | -0.44 | -0.44 |
| 284.37 | 1.55 | 1.55 |
| 298.39 | 1.58 | 1.58 |
| 312.42 | 1.45 | 1.45 |
| 269.35 | 1.48 | 1.48 |
| 283.38 | 1.79 | 1.79 |
| 283.38 | 1.79 | 1.79 |
| 283.38 | 1.79 | 1.79 |
| 299.38 | 1.49 | 1.49 |
| 299.38 | 1.49 | 1.49 |
| 299.38 | 1.49 | 1.49 |
| 329.40 | 1.49 | 1.49 |
| 303.80 | 2.13 | 2.13 |
| 303.80 | 2.13 | 2.13 |
| 395.25 | 2.08 | 2.08 |
| 395.25 | 2.08 | 2.08 |
| 308.39 | 1.66 | 1.66 |
| 324.39 | 1.36 | 1.36 |
| 370.46 | 3.02 | 3.02 |